Optical coherence tomography device

Patent metadata

Field	Value
Publication number	US-10718601-B2
Application number	US-201815899575-A
Country	US
Kind code	B2
Filing date	Feb 20, 2018
Priority date	Dec 13, 2013
Publication date	Jul 21, 2020
Grant date	Jul 21, 2020

Abstract

An optical coherence tomography device provided with: an OCT optical system configured to output OCT signal; and an analysis processing unit configured to process the OCT signal and generate motion contrast data of the specimen. The analysis processing unit is provided with: a first image data generation unit configured to process multiple OCT signals to generate first image data representing phase difference information of the multiple OCT signals, and a second image data generation unit configured to process the OCT signal to generate second image data representing amplitude information of the OCT signal. The analysis processing unit generates the motion contrast data based on the phase difference information in the first image data and the amplitude information in the second image data.

First claim

What is claimed is:

1. An optical coherence tomography device comprising:
an OCT optical system configured to detect measurement light irradiated onto a specimen and a reference light and output OCT signal based on the measurement light and the reference light; and
an analysis processing unit configured to process the OCT signal and generate motion contrast data of the specimen,
wherein the analysis processing unit comprises:
a first image data generation unit configured to generate first motion contrast image data by applying first analysis processing on the OCT signal; and
a second image data generation unit configured to generate second motion contrast image data by applying second analysis processing that is different from the first analysis processing on the OCT signal, and
wherein the analysis processing unit applies the second motion contrast image data as a filter onto the first motion contrast image data to remove an artifact at a high reflection portion.

2. The optical coherence tomography device according to claim 1 , wherein the analysis processing unit applies to the first motion contrast image data a weight based on the second motion contrast image data.

3. The optical coherence tomography device according to claim 1 , wherein the high reflection portion is a nerve fiber layer (NFL).

4. The optical coherence tomography device according to claim 1 ,
wherein the first image data generation unit generates a Doppler OCT image as the first motion contrast image data.

5. The optical coherence tomography device according to claim 1 ,
wherein the second image data generation unit processes the multiple OCT signals which is a plurality of OCT signals output from the OCT optical system being obtained at a different timing for the same position on the specimen and generates, as the second motion contrast image data, image data representing difference between a first vector based on phase information and the amplitude information of a first OCT signal selected from the multiple OCT signals and a second vector based on phase information and the amplitude information of a second OCT signal selected from the multiple OCT signals.

6. The optical coherence tomography device according to claim 1 ,
wherein the analysis processing unit applies, to one of the first motion contrast image data and the second motion contrast image data a filter based on another one of the first motion contrast image data and the second motion contrast image data.

7. The optical coherence tomography device according to claim 1 ,
wherein the analysis processing unit applies, to one of the first motion contrast image data and the second motion contrast image data a mask based on another one of the first motion contrast image data and the second motion contrast image data.

8. The optical coherence tomography device according to claim 1 ,
wherein the analysis processing unit obtains luminance with respect to each pixel of the motion contrast data by computing the phase difference information in the first motion contrast image data generated by the first image data generation unit and the amplitude information in the second motion contrast image data generated by the second image data generation unit.

9. The optical coherence tomography device according to claim 8 ,
wherein the analysis processing unit obtains the luminance with respect to each pixel of the motion contrast data by multiplying the phase difference information in the first motion contrast image data generated by the first image data generation unit and the amplitude information in the second motion contrast image data generated by the second image data generation unit.

10. The optical coherence tomography device according to claim 1 ,
wherein at least one of the multiple OCT signals is utilized as the OCT signal from which the second image data generation unit generates the second motion contrast image data.

11. The optical coherence tomography device according to claim 1 further comprising:
a control unit configured to control the OCT optical system to output at least two frames of OCT signals being obtained at a different timing for the same position on the specimen as the multiple OCT signals from which the first motion contrast image data is generated by the first image data generation unit.

12. The optical coherence tomography device according to claim 1 further comprising:
a control unit configured to control the OCT optical system to output at least two frames of OCT signals being obtained at a different timing for the same position on the specimen as the OCT signal from which the second motion contrast image data is generated by the second image data generation unit.

13. The optical coherence tomography device according to claim 1 ,
wherein the second image data generation unit generates the second motion contrast image data by processing the multiple OCT signals which is a plurality of OCT signals output from the OCT optical system being obtained at a different timing for the same position on the specimen.

14. The optical coherence tomography device according to claim 13 , wherein the first image data generation unit and the second image data generation unit generate the first motion contrast image data and the second motion contrast image data from the same set of the OCT signals.

15. The optical coherence tomography device according to claim 13 , wherein the first image data generation unit generates the first motion contrast image data as a Doppler OCT image being obtained from a phase difference of the multiple OCT signals, and
wherein the second image data generation unit generates the second motion contrast image data as a vector difference image obtained from a vector difference of the multiple OCT signals.

Assignees

• Nidek Kk

Inventors

• Takeno Naoki
• Hanebuchi Masaaki
• Furuuchi Yasuhiro
• Namiki Hajime

Classifications

• A61B5/0066

  Optical coherence imaging · CPC title

• G06T2207/10101

  Optical tomography; Optical coherence tomography [OCT] · CPC title

• A61B3/0025

  characterised by electronic signal processing, e.g. eye models · CPC title

• A61B5/7203

  for noise prevention, reduction or removal · CPC title

• G01B9/02091 Primary

  Tomographic interferometers, e.g. based on optical coherence · CPC title