Triptolide prodrugs
US-9150600-B2 · Oct 6, 2015 · US
Glucose conjugates of triptolide, analogs and uses thereof
US10695319B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10695319-B2 |
| Application number | US-201716074750-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 3, 2017 |
| Priority date | Feb 4, 2016 |
| Publication date | Jun 30, 2020 |
| Grant date | Jun 30, 2020 |
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Abstract
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Provided are compounds generated by conjugation of triptolide with glucose to form glucose-triptolide conjugates, provides compounds with effective anti-proliferative activity and improved tolerability as compared to naturally occurring triptolide compounds.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound of Formula I: T&A-L 1 -Sugar (I) wherein the T&A moiety is triptolide or one of its analogs, and can be selected from compounds 1 to 18: wherein L 1 can be sel…
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Cross-Sectional Technologies · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- A61K31/365Primary
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US10695319B2 cover?
- Provided are compounds generated by conjugation of triptolide with glucose to form glucose-triptolide conjugates, provides compounds with effective anti-proliferative activity and improved tolerability as compared to naturally occurring triptolide compounds.
- Who is the assignee on this patent?
- Univ Johns Hopkins, Shanghai Inst Organic Chemistry Cas
- What technology area does this patent fall under?
- Primary CPC classification A61K31/365. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jun 30 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).