Air shot detection

Patent metadata

Field	Value
Publication number	US-10688255-B2
Application number	US-201715498903-A
Country	US
Kind code	B2
Filing date	Apr 27, 2017
Priority date	Apr 29, 2016
Publication date	Jun 23, 2020
Grant date	Jun 23, 2020

Abstract

A medication injection device includes a barrel and a plunger disposed to dispense a fluid from the barrel. A dosage tracking system is coupled to output data indicative of the fluid dispensed. A controller is disposed within the medication injection device and coupled to receive the data from the dosage tracking system. The controller includes logic that when executed by the controller causes the controller to perform operations including determining, based on the data, whether an air shot event occurred while dispensing the fluid.

First claim

What is claimed is:

1. A medication injection device, comprising:
a plunger configured to fit, at least partially, within a barrel to dispense a fluid from the barrel;
a dosage tracking system configured to output data indicative of an amount the fluid dispensed, wherein the dosage tracking system is disposed in a plunger head of the medication injection device and includes an ultrasonic transducer oriented to emit ultrasonic signals through the fluid along a length of the barrel and to receive reflected ultrasonic signals when the plunger is positioned within the barrel, and wherein the data is indicative of a time of flight of the ultrasonic signals; and
a controller disposed within the medication injection device and coupled to the dosage tracking system to receive the data output from the dosage tracking system, wherein the controller includes logic that when executed by the controller causes the controller to perform operations including:
determining, based on the data, whether an air shot event occurred while dispensing the fluid, including:
measuring a distance traveled by the plunger head based upon the time of flight of the ultrasonic signals; and
determining that the air shot event occurred when the distance traveled by the plunger head is below a threshold distance.

2. The medication injection device of claim 1 , wherein the air shot event includes a fluid dispensing event where the fluid is deemed not to have been injected into a body.

3. The medication injection device of claim 1 , wherein the dosage tracking system further includes an orientation tracker to calculate an orientation of the medication injection device and to output an indication of the orientation in the data, and wherein determining, based on the data, whether the air shot event occurred while dispensing the fluid further comprises:
determining that the air shot event occurred when a dispensing end of the medication injection device is pointing upwards while dispensing the fluid.

4. The medication injection device of claim 1 , wherein determining, based on the data, whether the air shot event occurred while dispensing the fluid further comprises:
measuring quantities of the fluid dispensed during a sequence of fluid dispensing events including a first fluid dispensing event and a second fluid dispensing event, the first fluid dispensing event occurring prior the second fluid dispensing event, wherein the quantities include a first quantity of the fluid from the first fluid dispensing event and a second quantity of the fluid from the second fluid dispensing event;
comparing the first quantity of the first fluid dispensing event to the second quantity of the second fluid dispensing event; and
determining that the first fluid dispensing event is an occurrence of the air shot event when the first quantity of the fluid is smaller than the second quantity of the fluid.

5. The medication injection device of claim 1 , wherein determining, based on the data, whether the air shot event occurred while dispensing the fluid further comprises:
detecting a threshold period of inactivity of the medication injection device;
detecting a sequence of multiple fluid dispensing events following the threshold period of inactivity; and
determining that a first one of the multiple fluid dispensing events immediately following the threshold period of inactivity is an occurrence of the air shot event.

6. The medication injection device of claim 1 , wherein the dosage tracking system is further configured to sense a pressure inside the barrel and the data is indicative of the pressure, wherein determining, based on the data, whether the air shot event occurred while dispensing the fluid further comprises:
measuring rates of change of the pressure inside the barrel during a sequence of fluid dispensing events including a first fluid dispensing event occurring prior to a second fluid dispensing event;
comparing a first rate of pressure change during the first fluid dispensing event to a second rate of pressure change during the second fluid dispensing event; and
determining that the first fluid dispensing event is an occurrence of the air shot event when the first rate of pressure change is greater than the second rate of pressure change.

7. The medication injection device of claim 1 , wherein the dosage tracking system further includes an accelerometer configured to measure motion of the medication injection device and outputs an indication of the motion in the data, and wherein the controller includes additional logic that when executed by the controller causes the controller to perform further operations including:
identifying a tapping motion of the medication injection device as a bubble dislodge event; and
determining that a fluid dispensing event following the bubble dislodge event within a first threshold period of time is an occurrence of the air shot event.

8. The medication injection device of claim 1 , wherein the controller includes additional logic that when executed by the controller causes the controller to perform further operations including:
identifying a rolling motion of the medication injection device as a fluid mixing event; and
determining that a fluid dispensing event following the fluid mixing event within a threshold period of time is an occurrence of the air shot event.

9. The medication injection device of claim 1 , wherein the medication injection device includes at least one of an insulin pen or a syringe.

10. A method of tracking injections of a fluid delivered by a medication injection device, comprising:
measuring dispensing events from the medication injection device with a dosage tracking system;
sending ultrasonic signals with a transducer of the dosage tracking system through the fluid along a length of the medication injection device;
receiving reflected ultrasonic signals with the transducer, wherein data output from the dosage tracking system is indicative of a time of flight between emission and receipt of the ultrasonic signals;
tracking the data indicative of the dispensing events output from the dosage tracking system with a controller coupled to the dosage tracking system; and
determining based on the data whether one or more of the dispensing events includes an air shot event, including:
calculating a volume of fluid dispensed during each of the dispensing events based upon the time of flight of the ultrasonic signals; and
determining that the air shot event occurred during one or more of the dispensing events based on whether the volume of fluid dispensed during each of the dispensing events is less than a threshold volume.

11. The method of claim 10 , wherein the dosage tracking system includes an accelerometer, the method further comprising:
measuring motion of the medication injection device with the accelerometer;
identifying a tapping motion of the medication injection device as a bubble dislodge event; and
determining that a next one of the dispensing events following the bubble dislodge event includes the air shot event.

12. The method of claim 11 , further comprising:
identifying a rolling motion of the medication injection device as a fluid mixing event; and
determining that the next one of the dispensing events following the fluid mixing event and the bubble dislodge event includes the air shot event.

13. The method of claim 10 , further comprising:
calculating an orientation of the medication injection device with an orientation tracker included in the dosage tracking system, wherein the orientation of the medication injection device is included in the data received by the controller; and
determining t

Assignees

• Verily Life Sciences Llc

Inventors

• Mirov Russell
• Krasnow Benjamin David
• Smith Peter Howard
• Deyle Travis

Classifications

• A61M5/486

  Indicating injection pressure · CPC title

• A61M5/3146

  Priming, e.g. purging, reducing backlash or clearance · CPC title

• A61M2205/8212

  with means or measures taken for minimising energy consumption · CPC title

• A61M5/31511

  Piston or piston-rod constructions, e.g. connection of piston with piston-rod (A61M5/5066 takes precedence) · CPC title

• A61M2205/33

  Controlling, regulating or measuring · CPC title