Hydrophilic polymers with antimicrobial functionalities

Patent metadata

Field	Value
Publication number	US-10687530-B2
Application number	US-201715839388-A
Country	US
Kind code	B2
Filing date	Dec 12, 2017
Priority date	Dec 12, 2017
Publication date	Jun 23, 2020
Grant date	Jun 23, 2020

Abstract

Techniques regarding ionene and/or polyionene compositions with antimicrobial functionality and enhanced hydrophilicity are provided. For example, one or more embodiments can regard a chemical compound that can comprise an ionene unit, which can comprise a cation distributed along a degradable backbone. The degradable backbone can comprise a terephthalamide structure. The ionene unit can have antimicrobial functionality. Further, the chemical compound can comprise a hydrophilic functional group covalently bonded to the ionene unit. Also, the chemical compound can have carbohydrate mimetic functionality.

First claim

What is claimed is:

1. A polymer having a structure characterized by a formula selected from the group consisting of:

wherein n is a first integer greater than or equal to one and less than or equal to one thousand, and wherein m is a second integer greater than or equal to one and less than or equal to one thousand.

2. A method of making a polymer of formula (Ia):

wherein n is a first integer greater than or equal to one and less than or equal to one thousand, and wherein m is a second integer greater than or equal to one and less than or equal to one thousand;
the method comprising dissolving compounds of formulae (IIa), (IIIa), and (IVa)

in a solvent, and polymerizing the compounds of formulae (IIa), (IIIa), and (IVa) to form the polymer of formula (Ia).

3. The method of claim 2 , further comprising stirring the compounds of formulae (IIa), (IIIa), (IVa), and the solvent at a temperature greater than or equal to 15° C. and less than or equal to 150° C. for a period of time greater than or equal to 12 hours and less than or equal to 24 hours.

4. A method of making a polymer of formula (Ib):

wherein n is a first integer greater than or equal to one and less than or equal to one thousand, and wherein m is a second integer greater than or equal to one and less than or equal to one thousand;
the method comprising dissolving compounds of formulae (IIb), (IIIb), and (IVb)

in a solvent, and polymerizing the compounds of formulae (IIb), (IIIb), and (IVb) to form the polymer of formula (Ib).

5. The method of claim 4 , further comprising stirring the compounds of formulae (IIb), (IIIb), (IVb), and the solvent at a temperature greater than or equal to 15° C. and less than or equal to 150° C. for a period of time greater than or equal to 12 hours and less than or equal to 24 hours.

Assignees

• IBM
• Agency Science Tech & Res

Inventors

• Fevre Mareva B
• Hedrick James L
• Park Nathaniel H
• Piunova Victoria A
• Tan Pang Kern Jeremy
• Yang Yi Yan
• Zhang Mu San

Classifications

• C08L101/00 Primary

  Compositions of unspecified macromolecular compounds · CPC title

• A01N33/12

  Quaternary ammonium compounds · CPC title

• A01N43/50

  1,3-Diazoles; Hydrogenated 1,3-diazoles · CPC title

• A01N37/18 Primary

  containing the group —CO—N<, e.g. carboxylic acid amides or imides; Thio analogues thereof · CPC title

• C08G69/40

  Polyamides containing oxygen in the form of ether groups (C08G69/12, C08G69/32 take precedence) · CPC title