Controlling zinc oxide particle size for sunscreen applications

Patent metadata

Field	Value
Publication number	US-10682294-B2
Application number	US-201615082676-A
Country	US
Kind code	B2
Filing date	Mar 28, 2016
Priority date	Sep 3, 2015
Publication date	Jun 16, 2020
Grant date	Jun 16, 2020

Abstract

Zinc oxide compositions and methods for controlling zinc oxide particle size for sunscreen applications are provided herein. A method includes manipulating the size of multiple zinc oxide particles to be below a maximum threshold; selecting one or more media to be used in a sunscreen composition, wherein said selecting is based on the refractive index of each of the media; and integrating the manipulated zinc oxide particles into the selected media to create the sunscreen composition. A composition includes multiple zinc oxide particles, wherein each of the zinc oxide particles is (i) coated with an optical coating material and (ii) of a size that is below a maximum threshold; and a medium layer within which the zinc oxide particles are suspended, wherein the medium layer comprises a mixture of one or more media, and wherein each of the media has a refractive index below a predetermined threshold.

First claim

What is claimed is:

1. A method, comprising:
manipulating the size of each of multiple zinc oxide particles to be below a predetermined maximum threshold of 80 nanometers and above a predetermined minimum threshold of 30 nanometers;
coating each of the multiple zinc oxide particles with a coating of silicon dioxide of a user-controlled thickness based on a desired reduction of scattering of visible light by the multiple zinc oxide particles;
aggregating the multiple silicon dioxide-coated zinc oxide particles into one or more clusters, wherein each cluster is a size of greater than 200 nanometers, and wherein said aggregating comprises binding the silicon dioxide-coated zinc oxide particles within each of the clusters to a respective anchoring particle, wherein each respective anchoring particle comprises a zinc oxide particle having a modified surface, wherein the modified surface of each respective anchoring particle physically contacts each of the silicon dioxide-coated zinc oxide particles within the respective cluster via direct silicon dioxide-to-modified surface of anchoring particle contact, and wherein said binding comprises binding the silicon dioxide-coated zinc oxide particles to the anchoring particle such that the silicon dioxide-coated zinc oxide particles bound to the respective anchoring particle are optically separate from one another;
generating a first media layer by combining four media consisting of water, coconut oil, mineral oil, and polyparabens;
generating a second media layer by combining five media consisting of water, coconut oil, mineral oil, polyparabens, and shea butter; and
creating the sunscreen composition by (i) integrating the one or more clusters into the first media layer and (ii) applying the second media layer on the integration of the first composition formed by media layer and the one or more clusters.

2. A method, consisting of:
manipulating the size of each of multiple zinc oxide particles to be below a predetermined maximum threshold of 80 nanometers and above a predetermined minimum threshold of 30 nanometers;
coating each of the multiple zinc oxide particles with a coating of silicon dioxide of a user-controlled thickness based on a desired reduction of scattering of visible light by the multiple zinc oxide particles;
aggregating the multiple silicon dioxide-coated zinc oxide particles into one or more clusters, wherein each cluster is a size of greater than 200 nanometers, and wherein said aggregating comprises binding the silicon dioxide-coated zinc oxide particles within each of the clusters to a respective anchoring particle, wherein each respective anchoring particle comprises a zinc oxide particle having a modified surface, wherein the modified surface of each respective anchoring particle physically contacts each of the silicon dioxide-coated zinc oxide particles within the respective cluster via direct silicon dioxide-to-modified surface of anchoring particle contact, and wherein said binding comprises binding the silicon dioxide-coated zinc oxide particles to the anchoring particle such that the silicon dioxide-coated zinc oxide particles bound to the respective anchoring particle are optically separate from one another;
generating a first media layer by combining four media consisting of water, coconut oil, mineral oil, and polyparabens;
generating a second media layer by combining five media consisting of water, coconut oil, mineral oil, polyparabens, and shea butter; and
creating the sunscreen composition by (i) integrating the one or more clusters into the first media layer and (ii) applying the second media layer on the integration of the first composition formed by media layer and the one or more clusters.

Assignees

• IBM

Inventors

• Gershon Talia S
• Li Ning
• Sadana Devendra
• Todorov Teodor K

Classifications

• A61K8/27 Primary

  Zinc; Compounds thereof · CPC title

• A61K2800/413

  Nanosized, i.e. having sizes below 100 nm · CPC title

• A61K8/0241

  Containing particulates characterized by their shape and/or structure (see also A61K8/04, A61K8/11, and A61K8/14, further aspects are classified in A61K2800/40 and subcodes) · CPC title

• A61K8/25

  Silicon; Compounds thereof · CPC title

• A61K2800/262

  Transparent; Translucent · CPC title