Red fluorescent aldehyde dehydrogenase (aldh) substrate
US-2015369738-A1 · Dec 24, 2015 · US
Highly fluorescent pyrrole-BF2 chromophores
US10676489B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10676489-B2 |
| Application number | US-201816229368-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 21, 2018 |
| Priority date | Nov 20, 2013 |
| Publication date | Jun 9, 2020 |
| Grant date | Jun 9, 2020 |
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- Title
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Abstract
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Fluorescent chromophores nicknamed BOPHY are provided. The chromophores may be readily synthesized in two steps from readily available reagents via the coupling of a pyrrole aldehyde or ketone with hydrazine, followed by reaction with BF 3 . The resultant symmetric and dimeric tetracycle is comprised of two BF 2 units in six-member chelate rings, appended by pyrrole units on the periphery. The quantum yield of fluorescence for the unmodified compound and the tetramethyl variant are near unity, with values 95 and 92% respectively in CH 2 Cl 2 .
First claim
Opening claim text (preview).
What is claimed is: 1. A compound defined by the following structure: 2. A functionalizable compound defined by the following structure: wherein R is H or an aromatic group. 3. The compound of claim 2 , wherein the aromatic group is a benzene ring. 4. The compound of claim 2 , wherein the aromatic group is an azole group. 5. The compound of claim 2 , wherein the aromatic group is a thiophene ring.
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Classifications
comprising an organic dye as the active light absorbing material, e.g. adsorbed on an electrode or dissolved in solution · CPC title
Organic tenebrescent materials · CPC title
Electricity · mapped topic
Measuring or testing processes involving enzymes, nucleic acids or microorganisms (measuring or testing apparatus with condition measuring or sensing means, e.g. colony counters, C12M1/34); Compositions therefor; Processes of preparing such compositions · CPC title
containing two or more nitrogen atoms (hydrazon dyes -CH=N-N- C09B26/02) · CPC title
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- What does patent US10676489B2 cover?
- Fluorescent chromophores nicknamed BOPHY are provided. The chromophores may be readily synthesized in two steps from readily available reagents via the coupling of a pyrrole aldehyde or ketone with hydrazine, followed by reaction with BF 3 . The resultant symmetric and dimeric tetracycle is comprised of two BF 2 units in six-member chelate rings, appended by pyrrole units on the periphery. The…
- Who is the assignee on this patent?
- Ziegler Christopher J, Tamgho Ingrid Suzy, Univ Akron
- What technology area does this patent fall under?
- Primary CPC classification C07F5/022. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Jun 09 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).