Cycloalkyl-linked diheterocycle derivatives
US-10125130-B2 · Nov 13, 2018 · US
US10676471B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10676471-B2 |
| Application number | US-201916416997-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 20, 2019 |
| Priority date | Apr 30, 2014 |
| Publication date | Jun 9, 2020 |
| Grant date | Jun 9, 2020 |
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The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein A, L, D, R 1 -R 15 , w, x, y, and z are defined herein. The novel cycloalkyl-linked diheterocycle derivatives that are useful in the treatment of abnormal cell growth, such as cancer, in mammals. The present invention also relates to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
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We claim: 1. A compound selected from the group consisting of or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical formulation comprising at least one compound of claim 1 , or a pharmaceutically acceptable salt thereof, and at least one pharmaceutically acceptable carrier, diluent, or excipient.
not condensed and containing further heterocyclic rings · CPC title
containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole (nicotine A61K31/465) · CPC title
not condensed and containing further heterocyclic rings · CPC title
by carboxylic acids, or sulfur or nitrogen analogues thereof · CPC title
not condensed and containing further heterocyclic rings · CPC title
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