CT value controller and anticancer agent degradation apparatus

Patent metadata

Field	Value
Publication number	US-10675495-B2
Application number	US-201815921192-A
Country	US
Kind code	B2
Filing date	Mar 14, 2018
Priority date	Jun 25, 2013
Publication date	Jun 9, 2020
Grant date	Jun 9, 2020

Abstract

A CT value controller includes a storage means, an input means, and a computing means. The storage means stores a function expressing a relative humidity and a CT value regarding a degradation degree of an anticancer agent, an assumed relative humidity, and a CT setting. The input means inputs a measured relative humidity and a measured ozone concentration at a time of degradation treatment of the anticancer agent. The computing means calculates a corrected CT value increment based on a difference between the measured relative humidity and the assumed relative humidity at every input of the relative humidity and the ozone concentration by using the function. The computing means determines a termination of the degradation treatment of the anticancer agent when an integrated CT value of the corrected CT value increments reaches the CT setting.

First claim

The invention claimed is:

1. A CT value controller comprising:
storing a function relating a relative humidity and a CT value to a degradation degree of an anticancer agent in degradation of the anticancer agent, the degradation being caused by ozone gas-containing air, and storing a CT setting (Ect) as a degradation termination point of said anticancer agent when a set relative humidity (H 1 ) is maintained during degradation treatment, wherein the CT value is a product of ozone concentration and a time interval;
the CT value controller being programmed so as to, at set sampling time intervals (Δt, Te),
take a relative humidity (H 2 ) measured by a hygrometer and an ozone concentration (Co) measured by an ozone concentration sensor,
obtain:
a CT value increment (ΔCT) calculated as a product of said set sampling interval (Δt, Te) and said ozone concentration (Co),
a first degradation degree (ΔRb) calculated from said set relative humidity (H 1 ), said CT value increment (ΔCT), and a difference in said function,
a second degradation degree (ΔRr) calculated from said relative humidity (H 2 ), said CT value increment (ΔCT), and the difference in said function,
a value (F, G) obtained by dividing said second degradation degree (ΔRr) by said first degradation degree (ΔRb), and
a corrected CT value increment (ΔCTr) calculated as a product of said CT value increment (ΔCT) and said value (F,G), and
determine termination of said degradation treatment when a CT value (CT 2 , Sct), obtained by adding said corrected CT value increment (ΔCTr), reaches said CT setting (Ect).

2. An anticancer agent degradation apparatus comprising:
a container for degradation treatment of said anticancer agent;
an ozone generator configured to generate ozone gas;
a humidifier configured to humidify an inside of said container;
a measurement apparatus configured to measure an ozone concentration in said container;
a measurement apparatus configured to measure a relative humidity in said container; and
the CT value controller according to claim 1 .

Assignees

• Tamura Teco Co Ltd
• Univ Kinki

Inventors

• Tamura Kozo
• Fukuda Yoshiyuki
• Ishiwata Shunji
• Taga Atsushi

Classifications

• A62D2101/28

  containing oxygen, sulfur, selenium or tellurium, i.e. chalcogen · CPC title

• A62D2101/22

  containing halogen · CPC title

• A62D2101/26

  containing nitrogen or phosphorus · CPC title

• A62D3/38 Primary

  by oxidation; by combustion · CPC title