Ophthalmic analysis apparatus and ophthalmic analysis method

Patent metadata

Field	Value
Publication number	US-10674909-B2
Application number	US-201715696855-A
Country	US
Kind code	B2
Filing date	Sep 6, 2017
Priority date	Sep 7, 2016
Publication date	Jun 9, 2020
Grant date	Jun 9, 2020

Abstract

An ophthalmic analysis apparatus for analyzing OCT motion contrast (MC) image data of a subject's eye acquired using an OCT apparatus for ophthalmology includes analysis process means for analyzing the OCT MC image data, in which the analysis process means generates OCT blood vessel change data including temporal change information in relation to a blood vessel region of the subject's eye based on first OCT MC image data and second OCT MC image data acquired at mutually different times.

First claim

What is claimed is:

1. An ophthalmic analysis method comprising:
acquiring first optical coherence tomography (OCT) MC (motion contrast) image data of a subject's eye and second OCT MC image data of the subject's eye using at least one OCT apparatus for ophthalmology, the first OCT MC image data and the second OCT MC image data being acquired at different times;
analyzing the acquired first OCT MC image data and second OCT MC image data to generate OCT blood vessel change data including temporal change information in relation to a blood vessel region of the subject's eye based on the first OCT MC image data and the second OCT MC image data; and
wherein, as the OCT blood vessel change data, OCT blood vessel increase-and-decrease data which includes temporal change information in relation to at least one of increase-and-decrease of a blood vessel region of the subject's eye is generated based on the first OCT MC image data and the second OCT MC image data.

2. The ophthalmic analysis method according to claim 1 , wherein
a position adjusting process is performed to adjust a position of the first OCT MC image data and a position of the second OCT MC image data in a depth direction, and
the OCT blood vessel change data is generated based on the first OCT MC image data and the second OCT MC image data on which the position adjusting process is performed.

3. The ophthalmic analysis method according to claim 1 , wherein corrects a brightness difference between the first OCT MC image data and the second OCT MC image caused by an influence of sensitivity attenuation in the depth direction is corrected.

4. An ophthalmic analysis method comprising:
acquiring first optical coherence tomography (OCT) MC (motion contrast) image data of a subject's eye and second OCT MC image data of the subject's eye using at least one OCT apparatus for ophthalmology, the first OCT MC image data and the second OCT MC image data being acquired at different times;
analyzing the acquired first OCT MC image data and second OCT MC image data to generate OCT blood vessel change data including temporal change information in relation to a blood vessel region of the subject's eye based on the first OCT MC image data and the second OCT MC image data; and
wherein OCT blood vessel increase-and-decrease data which includes the temporal change information in relation to the increase and the decrease of the blood vessel region of the subject's eye is generated based on the first OCT MC image data and the second OCT MC image data, and is displayed on a display unit in such a manner that increase of blood vessel region is different from the decrease of the blood vessel region in displaying forms.

5. The ophthalmic analysis method according to claim 1 , wherein the OCT blood vessel increase-and-decrease data includes the temporal change information in relation to at least one of vascularization and extinction of the blood vessel region of the subject's eye.

6. The ophthalmic analysis method according to claim 1 , wherein a segmentation result with respect to the first OCT MC image data is applied to the second OCT MC image data, and the OCT blood vessel change data in relation to a specific layer region is obtained.

7. The ophthalmic analysis method according to claim 1 , wherein in the OCT blood vessel change data, temporal change in relation to the blood vessel region of the subject's eye is divided in each section.

8. The ophthalmic analysis method according to claim 1 , wherein the OCT blood vessel change data includes the temporal change information in relation to the blood vessel region of the subject's eye in the specific layer region.

9. The ophthalmic analysis method according to claim 1 , wherein
the analysis the first OCT MC image data and the second OCT MC image data are analyzed by an image process to acquire at least one of analysis parameters in relation to the first OCT MC image data and the second OCT MC image data, and
at least one of the analysis parameters is displayed with the OCT blood vessel change data.

10. The ophthalmic analysis method according to claim 1 , wherein image data in which the OCT blood vessel change data is reflected to any one of the first OCT MC image data and the second OCT MC image data is displayed on a display unit.

11. The ophthalmic analysis method according to claim 1 , wherein the OCT blood vessel change data is generated based on a difference of luminance between first MC image data and second MC image data.

12. The ophthalmic analysis method according to claim 1 , wherein the first OCT MC image data and the second OCT MC image data acquired at different times are OCT MC image data of a fundus of the subject's eye.

13. An ophthalmic analysis apparatus comprising:
a processor; and
memory storing computer readable program, when executed by the processor, causing the ophthalmic analysis apparatus to execute:
acquiring first optical coherence tomography (OCT) MC (motion contrast) image data of a subject's eye and second OCT MC image data of the subject's eye using at least one OCT apparatus for ophthalmology, the first OCT MC image data and the second OCT MC image data being acquired at different times;
analyzing the acquired first OCT MC image data and second OCT MC image data to generate OCT blood vessel change data including temporal change information in relation to a blood vessel region of the subject's eye based on the first OCT MC image data and the second OCT MC image data; and
wherein, as the OCT blood vessel change data, OCT blood vessel increase-and-decrease data which includes temporal change information in relation to at least one of increase-and-decrease of a blood vessel region of the subject's eye is generated based on the first OCT MC image data and the second OCT MC image data.

14. A non-transitory computer readable recording medium storing a computer readable program, when executed by a processor of an ophthalmic analysis apparatus, causing the ophthalmic analysis apparatus to execute:
acquiring first optical coherence tomography (OCT) MC (motion contrast) image data of a subject's eye and second OCT MC image data of the subject's eye using at least one OCT apparatus for ophthalmology, the first OCT MC image data and the second OCT MC image data being acquired at different times;
analyzing the acquired first OCT MC image data and second OCT MC image data to generate OCT blood vessel change data including temporal change information in relation to a blood vessel region of the subject's eye based on the first OCT MC image data and the second OCT MC image data; and
wherein, as the OCT blood vessel change data, OCT blood vessel increase-and-decrease data which includes temporal change information in relation to at least one of increase-and-decrease of a blood vessel region of the subject's eye is generated based on the first OCT MC image data and the second OCT MC image data.

Assignees

• Nidek Kk

Inventors

• Kano Tetsuya
• Satake Norimasa
• Higuchi Yukihiro
• Furuuchi Yasuhiro

Classifications

• G06T2207/10028

  Range image; Depth image; 3D point clouds · CPC title

• A61B3/0025

  characterised by electronic signal processing, e.g. eye models · CPC title

• G06T15/04

  Texture mapping · CPC title

• A61B3/1241 Primary

  specially adapted for observation of ocular blood flow, e.g. by fluorescein angiography · CPC title

• G06T2207/30041

  Eye; Retina; Ophthalmic · CPC title