Gamma-aapeptides with potent and broad-spectrum antimicrobial activity
US-2015274782-A1 · Oct 1, 2015 · US
US10669241B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10669241-B2 |
| Application number | US-201916265662-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 1, 2019 |
| Priority date | Feb 17, 2017 |
| Publication date | Jun 2, 2020 |
| Grant date | Jun 2, 2020 |
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Described herein are compounds and formulations thereof that can bind PTEN. Also described herein are methods of using the compounds and formulations thereof that can bind PTEN. In some embodiments, the method can include administering an amount of a compound or formulation described herein to a subject in need thereof.
Opening claim text (preview).
We claim: 1. A compound having a structure according to Formula 1 where R 1 is H, where R 2 is where R 3 is where R 4 is or where R 3 and R 4 together form 2. The compound of claim 1 , wherein the compound is compound 15, 16, 17, 18, 19, 20, 21, 24, 25, 26, 27, 32, 33, 34, 35, or 47 C 78 H 116 N 16 O 11 S 2 (35) 3. The compound of claim 1 , wherein the compound is compound 5, 8, 9, 10, 11, 12, 13, 14, 38, 39, 40, or 43
with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members · CPC title
of a saturated carbon skeleton containing rings · CPC title
substituted additionally by nitrogen atoms, e.g. tryptophane · CPC title
having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms · CPC title
Antineoplastic agents · CPC title
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