Mucosal vaccines with chitosan adjuvant and meningococcal antigens
US-8926992-B2 · Jan 6, 2015 · US
Injectable vaccines against multiple meningococcal serogroups
US10668142B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10668142-B2 |
| Application number | US-201815962507-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 25, 2018 |
| Priority date | Jan 30, 2003 |
| Publication date | Jun 2, 2020 |
| Grant date | Jun 2, 2020 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
An injectable immunogenic composition comprising capsular saccharides from at least two of serogroups A, C, W135 and Y of Neisseria meningitidis , wherein said capsular saccharides are conjugated to carrier protein(s) and/or are oligosaccharides, and wherein (i) the composition comprises <50 μg meningococcal saccharide per dose, and/or (ii) the composition further comprises an antigen from one or more of: (a) serogroup B N. meningitidis ; (b) Haemophilus influenzae type B; and/or (c) Streptococcus pneumoniae . Saccharide antigens in the compositions are generally conjugated to a carrier.
First claim
Opening claim text (preview).
The invention claimed is: 1. A kit comprising (a) a lyophilized capsular saccharide of Neisseria meningitidis serogroup A conjugated to a carrier protein and (b) liquid capsular saccharides of Neisseria meningitidis serogroups C, W135 and Y each conjugated to a carrier protein, wherein each of the conjugates is a separate conjugate for each of the serogroups A, C, Y and W135 and wherein reconstitution of the lyophilized capsular saccharide conjugate of the serogroup A Neisseria meningitidis with the liquid capsular saccharide conjugates of the serogroups C, Y and W135 Neisseria meningitidis produces an injectable composition comprising between about 10 micrograms and 25 micrograms of the capsular saccharides per dose of the composition and wherein the capsular saccharides of the Neisseria meningitidis serogroups A, C, W135 and Y are present at a 2:1:1:1 capsular saccharide weight ratio. 2. The kit of claim 1 , wherein the capsular saccharide of Neisseria meningtidis serogroup A is modified so that one or more hydroxyl groups of the capsular saccharide have been replaced with blocking groups.
Assignees
Inventors
Classifications
Combination vaccines based on whole cell diphtheria-tetanus-pertussis · CPC title
characterised by the linker · CPC title
characterised by the route of administration · CPC title
Multivalent vaccine · CPC title
Clostridium, e.g. Clostridium tetani · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US10668142B2 cover?
- An injectable immunogenic composition comprising capsular saccharides from at least two of serogroups A, C, W135 and Y of Neisseria meningitidis , wherein said capsular saccharides are conjugated to carrier protein(s) and/or are oligosaccharides, and wherein (i) the composition comprises <50 μg meningococcal saccharide per dose, and/or (ii) the composition further comprises an antigen from one…
- Who is the assignee on this patent?
- Glaxosmithkline Biologicals Sa
- What technology area does this patent fall under?
- Primary CPC classification A61K39/095. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Jun 02 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 1 related publication on this page (citations in our corpus or others sharing the same primary CPC).