Guidewire with an atraumatic clot-circumventing configured distal end for use in an endovascular medical system

Patent metadata

Field	Value
Publication number	US-10667833-B2
Application number	US-201816003527-A
Country	US
Kind code	B2
Filing date	Jun 8, 2018
Priority date	Jun 8, 2018
Publication date	Jun 2, 2020
Grant date	Jun 2, 2020

Abstract

An endovascular medical system for use with a clot located in a target vessel. The system including a guidewire formed by a core wire. The guidewire extending in a longitudinal direction from a proximal end to an opposite atraumatic clot-circumventing configured distal end; and a lateral direction of the atraumatic clot-circumventing configured distal end of the guidewire being defined transverse to the longitudinal direction of the guidewire. The atraumatic clot-circumventing configured distal end is designed to prevent injury to an inner wall of the target vessel and prohibit insertion of any portion of the guidewire into a perforator vessel.

First claim

What is claimed is:

1. A method for using an endovascular medical system for use with a clot located in a target vessel, the endovascular medical system including a microcatheter having a lumen defined longitudinally therethrough from its proximal end to its opposite distal end, the lumen having an inner diameter; the endovascular medical system further including a guidewire formed by a core wire and receivable through the lumen of the microcatheter, the guidewire extending in a longitudinal direction from a proximal end to an opposite atraumatic clot-circumventing configured distal end; a lateral direction of the atraumatic clot-circumventing configured distal end of the guidewire being defined transverse to the longitudinal direction of the guidewire; wherein the atraumatic clot-circumventing configured distal end is configured to prevent injury to an inner wall of the target vessel and prohibit insertion of any portion of the guidewire into a perforator vessel; the method comprising the steps of:
advancing the atraumatic clot-circumventing configured distal end of the guidewire through the target vessel to a location facing a proximal side of the clot;
tracking the microcatheter over the guidewire received within the lumen of the microcatheter to the location facing the proximal side of the clot;
passing the atraumatic clot-circumventing configured distal end of the guidewire between the inner wall of the target vessel and the clot from a position on the proximal side of the clot to a position facing a distal side of the clot, without any portion of the atraumatic clot-circumventing configured distal end of the guidewire penetrating the clot;
guiding the microcatheter over the guidewire received within the lumen of the microcatheter to the position facing the distal side of the clot.

2. The method according to claim 1 , wherein the atraumatic clot-circumventing configured distal end satisfies the following conditions:
(i) the atraumatic clot-circumventing distal end of the guidewire in a non-compressed state having a widest width in the lateral direction of the atraumatic clot-circumventing configured distal end of the guidewire greater than twice the inner diameter of the lumen of the microcatheter;
(ii) when advanced in the target vessel between the inner wall of the target vessel and the clot, the atraumatic clot-circumventing configured distal end of the guidewire is conformable in the lateral direction complementary to a contour of the inner wall of the target vessel; and
(iii) wherein the widest width in the lateral direction of the atraumatic clot-circumventing configured distal end of the guidewire, when subject to application of an external force, is reduceable in diameter to be receivable within the lumen of the microcatheter.

3. The method according to claim 1 , wherein the atraumatic clot-circumventing configured distal end of the guidewire is a flattened distal portion of the core wire having a planar geometric shape and thickness smaller than a diameter of a remaining non-flattened portion of the core wire.

4. The method according to claim 1 , wherein the atraumatic clot-circumventing configured distal end of the guidewire is the core wire pre-formed or pre-shaped into a geometric shape.

5. The method according to claim 4 , wherein the geometric shape is a closed loop.

6. The method according to claim 4 , wherein the closed loop forms a lemon-shape.

7. The method according to claim 4 , wherein the geometric shape of the atraumatic clot-circumventing configured distal end while in a non-compressed state not subject to application of an external mechanical force is an open loop forming a curved section greater than 180° having a free terminating end; and while in the non-compressed state not subject to an external mechanical force, the atraumatic clot-circumventing configured distal end is in a prolapsed configuration.

8. The method according to claim 1 , further comprising the step of, when withdrawn back into the lumen of the microcatheter, curling in a lateral direction the atraumatic clot-circumventing configured distal end of the guidewire thereby reducing its diameter to be less than the inner diameter of the lumen of the microcatheter.

9. The method according to claim 1 , wherein the guidewire and the atraumatic clot-circumventing configured distal end are separate components assembled together.

Assignees

• Neuravi Ltd

Inventors

• Vale David
• Gilvarry Michael

Classifications

• A61B2017/22044

  with a pointed tip · CPC title

• A61B2017/2212

  having a closed distal end, e.g. a loop · CPC title

• A61B17/221 Primary

  Gripping devices in the form of loops or baskets {for gripping calculi or similar types of obstructions (surgical snare instruments A61B17/32056)} · CPC title

• A61B2017/22094

  for crossing total occlusions, i.e. piercing · CPC title

• A61B17/22 Primary

  Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for · CPC title