Method for producing compound and compound production system used in production method

Patent metadata

Field	Value
Publication number	US-10662449-B2
Application number	US-201515311794-A
Country	US
Kind code	B2
Filing date	Jul 3, 2015
Priority date	Jul 10, 2014
Publication date	May 26, 2020
Grant date	May 26, 2020

Abstract

This method for producing a compound uses a continuous tank reactor which is provided with two or more reaction tanks for producing the compound and with a reaction liquid feeding pipe that feeds a reaction liquid from an upstream reaction tank to a downstream reaction tank, said method being characterized in that the Reynold's number of the reaction liquid that flows in the reaction liquid feeding pipe is configured to be 1800-22000. Furthermore, this compound production system is used in said method for producing a compound, and is formed by housing at least one of the reaction tanks in a portable container.

First claim

The invention claimed is:

1. A method for producing acrylamide in a continuous tank reactor, the method comprising:
flowing a reaction liquid, which comprises acrylonitrile, a biocatalyst, and an acid or alkali solution from an upstream reaction tank to a downstream reaction tank via a reaction liquid feeding pipe at a Reynolds number of 2,000 to 20,000, wherein the continuous tank reactor comprises two or more reaction tanks, and the reaction liquid feeding pipe connects the upstream reaction tank to the adjacent downstream reaction tank, and a height of a liquid surface of the downstream reaction tank is lower than the height of the liquid surface of the upstream reaction tank,
wherein the method produces acrylamide.

2. The method according to claim 1 , wherein at least one tank of the reaction tanks is accommodated in a portable container, and a value obtained by dividing an inner volume (m 3 ) of the portable container by a flow rate (m 3 /hour) of the reaction liquid flowing in the at least one reaction tank accommodated in the portable container is from 5 to 70 hours.

3. The method according to claim 1 , further comprising:
supplying an acrylonitrile-containing liquid to at least one tank of the reaction tanks;
supplying raw water to at least one tank of the reaction tanks; and
supplying a biocatalyst aqueous dispersion to at least one tank of the reaction tanks.

4. The method according to claim 1 , further comprising:
supplying an acrylonitrile-containing liquid, raw water and a biocatalyst aqueous dispersion to at least a tank positioned at the most upstream side of the reaction liquid.

5. The method of claim 1 , wherein at least one tank of the reaction tanks is accommodated in a portable container, and wherein a total volume of the at least one tank accommodated in the portable container is ⅙ to ⅗ of an inner volume of the portable container.

6. The method of claim 1 , wherein at least one tank of the reaction tanks is accommodated in a portable container, and wherein another portable container is disposed on the portable container in which the at least one tank of the reaction tanks is accommodated.

7. The method of claim 1 , wherein at least one tank of the reaction tanks is accommodated in a portable container, and wherein a volume of the at least one reaction tank accommodated in the portable container is from 6.4 m 3 to 22.9 m 3 .

8. The method of claim 1 , wherein the liquid surface height difference between the reaction tank and the adjacent reaction tank is 0.05 to 10 cm.

9. The method of claim 1 , wherein the liquid surface height difference between the reaction tank and the adjacent reaction tank is 0.1 to 3 cm.

Assignees

• Mitsubishi Chem Corp
• Mitsubishi Chem Eng Corp

Inventors

• Kano Makoto
• Kariya Takamitsu
• Banba Hiroyasu
• Mawatari Tomohiko
• Kato Takeshi
• Hirachi Tsutomu
• Tachibana Keizo
• KAMIDE Masahiro
• MORIMOTO Megumu

Classifications

• C12M23/58

  Reaction vessels connected in series or in parallel (combinations of bioreactors with other apparatus, C12M43/00) · CPC title

• C12P13/02 Primary

  Amides, e.g. chloramphenicol {or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes (peptides C12P21/00 or C07K)} · CPC title

• C12M27/02

  Stirrer or mobile mixing elements · CPC title

• C12M1/02

  with agitation means; with heat exchange means · CPC title

• C12M21/18

  Apparatus specially designed for the use of free, immobilized or carrier-bound enzymes · CPC title