Alantolactone/isoalantolactone spiro aryl isoxazoline compounds

US10662201B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10662201-B2
Application numberUS-201816167590-A
CountryUS
Kind codeB2
Filing dateOct 23, 2018
Priority dateDec 15, 2017
Publication dateMay 26, 2020
Grant dateMay 26, 2020

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A compound of chemical formula I: or chemical formula II: or a pharmaceutical acceptable salt thereof is disclosed. R 1 , R 2 , R 3 , and R 4 are independently H, halogen, nitro, hydroxyl, cyano, benzyloxy, C 1 -C 8 straight or branched alkyl, C1-C8 straight or branched haloalkyl, C 1 -C 8 straight or branched alkoxy.

First claim

Opening claim text (preview).

What is claimed is: 1. A compound of chemical formula I or II: or a pharmaceutical acceptable salt thereof, wherein R 1 , R 2 , R 3 , and R 4 are independently H, halogen, nitro, hydroxyl, cyano, benzyloxy, C 1 -C 8 straight or branched alkyl, C 1 -C 8 straight or branched haloalkyl, C 1 -C 8 straight or branched alkoxy. 2. The compound of claim 1 , wherein R 1 is H, R 2 is F, R 3 is H, and R 4 is H. 3. The compound of claim 1 , wherein R 1 is H, R 2 is H, R 3 is F, and R 4 is H. 4. The compound of claim 1 , wherein R 1 is H, R 2 is H, R 3 is CF 3 , and R 4 is H. 5. The compound of claim 1 , wherein R 1 is H, R 2 is H, R 3 is CN, and R 4 is H. 6. The compound of claim 1 , wherein R 1 is F, R 2 is H, R 3 is CN, and R 4 is H. 7. The compound of claim 1 , wherein R 1 is H, R 2 is NO 2 , R 3 is F, and R 4 is H. 8. The compound of claim 1 , wherein R 1 is H, R 2 is CN, R 3 is H, and R 4 is F.

Assignees

Inventors

Classifications

  • Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] · CPC title

  • Antiasthmatics · CPC title

  • C07D498/10Primary

    Spiro-condensed systems · CPC title

  • condensed with heterocyclic ring systems, e.g. clavulanic acid · CPC title

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What does patent US10662201B2 cover?
A compound of chemical formula I: or chemical formula II: or a pharmaceutical acceptable salt thereof is disclosed. R 1 , R 2 , R 3 , and R 4 are independently H, halogen, nitro, hydroxyl, cyano, benzyloxy, C 1 -C 8 straight or branched alkyl, C1-C8 straight or branched haloalkyl, C 1 -C 8 straight or branched alkoxy.
Who is the assignee on this patent?
Liang Chengyuan, Ju Xingke, Tian Lei, and 6 more
What technology area does this patent fall under?
Primary CPC classification C07D498/10. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).