Selective androgen receptor modulator and methods of use thereof

US10662148B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10662148-B2
Application numberUS-201815887076-A
CountryUS
Kind codeB2
Filing dateFeb 2, 2018
Priority dateJun 7, 2004
Publication dateMay 26, 2020
Grant dateMay 26, 2020

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

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  7. Citations and related patents

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Abstract

Official abstract text for this publication.

This invention provides substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating, reducing the severity, reducing the incidence, or reducing cardiovascular failure in a subject suffering from Duchenne muscular dystrophy, comprising the step of administering to said subject a selective androgen receptor modulator (SARM) compound represented by the structure of formula S-(III): or its pharmaceutically acceptable salt. 2. The method of claim 1 , wherein said method further increases the physical function of said subject. 3. The method of claim 1 , wherein said method further increases the quality of life of said subject. 4. The method of claim 1 , wherein said method increases the survival of said subject. 5. The method of claim 1 , wherein said method further delays onset or improves symptoms of respiratory function.

Assignees

Inventors

Classifications

  • C07C255/54Primary

    containing cyano groups and etherified hydroxy groups bound to the carbon skeleton · CPC title

  • A61K31/277Primary

    having a ring, e.g. verapamil · CPC title

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Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US10662148B2 cover?
This invention provides substituted acylanilide compounds and uses thereof in treating a variety of diseases or conditions in a subject including, inter alia, a muscle wasting disease and/or disorder such as Duchenne muscular dystrophy or Becker muscular dystrophy.
Who is the assignee on this patent?
Univ Tennessee Res Found
What technology area does this patent fall under?
Primary CPC classification C07C255/54. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue May 26 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).