Imaging composition and uses thereof
US-10398660-B2 · Sep 3, 2019 · US
Imaging composition and uses thereof
US10653649B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10653649-B2 |
| Application number | US-201916511577-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 15, 2019 |
| Priority date | Oct 16, 2014 |
| Publication date | May 19, 2020 |
| Grant date | May 19, 2020 |
How to read this patent
A practical reading order for non-experts. Skip the full description unless you need deep technical detail.
- Title
What the patent document calls the invention.
- Abstract
A short plain-language summary of the technical disclosure.
- Assignees and inventors
Who owns or filed the patent and who is credited as inventor.
- Key dates
Filing, priority, publication, and grant dates set the timeline.
- First independent claim
The legal scope of protection — read this for what is actually claimed.
- CPC / IPC classifications
Technology tags used to group this patent with similar filings.
- Citations and related patents
Prior art links and similar publications in this corpus.
Abstract
Official abstract text for this publication.
The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging agents when bound to an appropriate metal centre, particularly for the imaging of tumours.
First claim
Opening claim text (preview).
The invention claimed is: 1. A conjugate of: a compound of formula (I): or a pharmaceutically acceptable salt thereof, and a molecule to target a tissue or tumour, wherein L is a leaving group selected from azide, halogen, cyanate and OR, wherein R is selected from C 1 to C 10 alkyl, C 1 to C 10 heteroalkyl, C 2 to C 10 alkene, C 2 to C 10 alkyne, and aryl, each of which is optionally substituted. 2. The conjugate of claim 1 , wherein L is OR. 3. The conjugate of claim 2 , wherein R is C 1 to C 6 alkyl. 4. The conjugate of claim 2 , wherein OR is selected from O-p-toluenesulfonate, O-methanesulfonate, O-trifluoromethanesulfonate, O-benzenesulfonate, and O-m-nitrobenzenesulfonate. 5. The conjugate of claim 1 , wherein the target molecule is a polypeptide. 6. The conjugate of claim 1 , wherein the molecule is a peptide. 7. The conjugate of claim 6 , wherein the peptide is a targeting peptide. 8. The conjugate of claim 7 , wherein the targeting peptide is selected from a cyclic RGD sequence, bombesin and glu-N(CO)N-lys PSMA.
Assignees
Inventors
Classifications
Sulfur atoms · CPC title
Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals · CPC title
to an acyclic saturated chain · CPC title
Sulfur atoms (C07D215/24 takes precedence) · CPC title
with hetero atoms directly attached to the ring nitrogen atom · CPC title
Patent family
Related publications grouped by family.
External sources
Frequently asked questions
Answers are generated from the same data shown on this page.
- What does patent US10653649B2 cover?
- The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging agents when bound to an appropriate metal centre, particularly for the imaging of tumours.
- Who is the assignee on this patent?
- Univ Melbourne
- What technology area does this patent fall under?
- Primary CPC classification A61K31/18. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue May 19 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).