Preparation of compounds from levulinic acid

Patent metadata

Field	Value
Publication number	US-10647670-B2
Application number	US-201615547041-A
Country	US
Kind code	B2
Filing date	Jan 29, 2016
Priority date	Jan 30, 2015
Publication date	May 12, 2020
Grant date	May 12, 2020

Abstract

The present invention provides a method of making carboxylic acids from levulinic acid, such as succinic acid and 3-hydroxypropanoic acid, by reacting levulinic acid with an oxidant such as hydrogen peroxide under acidic or basic conditions.

First claim

What is claimed is:

1. A method of preparing a carboxylic acid, comprising:
forming a reaction mixture comprising levulinic acid, an oxidant selected from peroxides, and an acid, wherein the acid is trifluoroacetic acid, under conditions suitable to prepare the carboxylic acid, wherein the carboxylic is succinic acid, wherein the reaction mixture is free of an oxidizing metal catalyst, and
heating the reaction mixture at a temperature of from about 30° C. to about 100° C., thereby preparing the succinic acid.

2. The method of claim 1 , wherein the oxidant is hydrogen peroxide.

3. The method of claim 1 , wherein the acid is trifluoroacetic acid, and the oxidant is hydrogen peroxide; and
the reaction mixture is heated at a temperature of from about 50° C. to about 100° C., thereby preparing succinic acid.

Assignees

• Univ California

Inventors

• Mascal Mark
• Dutta Saikat
• Wu Linglin

Classifications

• C07C409/04

  the carbon atom being acyclic · CPC title

• C07C407/00 Primary

  Preparation of peroxy compounds · CPC title

• C07B41/08

  of carboxyl groups or salts, halides or anhydrides thereof · CPC title

• C07C51/285

  with peroxy-compounds · CPC title

• C07B41/14

  of peroxy of hydroperoxy groups · CPC title