Compositions and method for viscosity-increasable dental composites

Patent metadata

Field	Value
Publication number	US-10646409-B2
Application number	US-201815904919-A
Country	US
Kind code	B2
Filing date	Feb 26, 2018
Priority date	Mar 3, 2017
Publication date	May 12, 2020
Grant date	May 12, 2020

Abstract

Described is a stable, two-component low viscosity composite that is capable to achieve excellent adaptation to walls/substrates due to its intrinsic flow ability and is also capable of rapid viscosity increasing and being manipulated prior to cure by light upon mixing of such a two-paste composite due to one distinguished reaction promoting partial network formation thus to allow a practitioner further manipulate a firm composite. Upon a completed manipulation by the practitioner, such a mixed material should be readily cured into final solid form by using conventional curing light.

First claim

I claim:

1. A two-component flowable dental composition capable of being cured in a two-stage curing process, said dental composition comprising: (a) a base paste comprising a polythiol and a methacrylate, and (b) a catalyst paste comprising a polyene, a methacrylate resin, a photoinitiator and a base catalyst;
wherein the polyene is selected from the group consisting of tricyclo[5.2.1.0 2,6 ]decanedimethanol diacrylate, pentaerythritol tetraacrylate and polyacrylates;
wherein the base catalyst is capable of promoting thiol-ene Michael-addition at room temperature upon the base paste/catalyst paste mixing in stage one of the two-stage curing process; and the photoinitiator is capable of promoting radical addition in stage two of the two stage curing process.

2. The dental composition according to claim 1 , wherein the base paste includes ethoxylated bisphenol A dimethacrylate or tri(ethylene glycol) dimethacrylate.

3. The dental composition according to claim 1 , wherein the polythiol includes pentaerythritol tetra(3-mercaptopropionate) or ethoxylated-trimethylolpropan tri(3-mercaptopropionate.

4. The dental composition according to claim 1 , wherein the photoinitiator includes camphorquinone, 2,4,6-trimethylbenzoyl diphenylphosphine oxide or mixtures thereof.

5. The dental composition according to claim 1 , wherein base paste further comprises an additive.

6. The dental composition according to claim 5 , wherein the additive includes lauryl gallate, pyrogallol, tris (2,4-di-tert-butylphenyl)phosphite or triphenylphosphite.

7. The dental composition according to claim 1 , wherein the composition is capable of being further polymerized by irradiation of a light of from 320 nm to 480 nm.

8. The dental composition according to claim 1 , wherein the base paste and catalyst paste further includes a glass filler in a concentration of from 10 to 70 weight percent based on the total weight of the composition.

9. The dental composition according to claim 1 , wherein the base paste and catalyst paste further comprises a nanosilica.

10. The dental composition according to claim 1 , wherein the base catalyst is selected from the group consisting of triethyl amine, 1,8-diazabicyclo[5,4,0] undec-7-ene, and 1,4-diazabicyclo[2,2,2]-octane.

11. The dental composition according to claim 1 , wherein the flowable dental composition is capable of achieving controlled viscosity increase upon base paste/catalyst paste mixing due to thiol-ene Michael addition prior to light irradiation.

12. A flowable composite produced by curing the two-component flowable dental composition according to claim 1 in the two-stage curing process.

Assignees

• Dentsply Sirona Inc

Inventors

• Jin Xiaoming

Classifications

• A61K6/61 Primary

  Cationic, anionic or redox initiators · CPC title

• A61K6/887 Primary

  Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds · CPC title

• A61K6/62

  Photochemical radical initiators · CPC title

• A61K6/838

  Phosphorus compounds, e.g. apatite · CPC title

• A61K6/891

  Compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds · CPC title