Diamine compound, and heat-resistant resin or heat-resistant resin precursor using same
US-2017334837-A1 · Nov 23, 2017 · US
Histone acetyltransferase activators and uses thereof
US10640457B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10640457-B2 |
| Application number | US-201213493490-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 11, 2012 |
| Priority date | Dec 10, 2009 |
| Publication date | May 5, 2020 |
| Grant date | May 5, 2020 |
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- Title
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- Abstract
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Abstract
Official abstract text for this publication.
The invention provides for a method for screening compounds that bind to and modulate a histone acetyltransferase protein. The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a HAT-activating compound to a subject.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound having the following structure or a pharmaceutically acceptable salt or hydrate thereof. 2. The compound of claim 1 , wherein the compound is a pharmaceutically acceptable salt. 3. The compound of claim 2 , wherein the pharmaceutically acceptable salt is an acid addition salt. 4. The compound of claim 3 , wherein the compound is a hydrochloride salt.
Assignees
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Classifications
the ring being saturated · CPC title
involving transferase · CPC title
Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates · CPC title
X or Y being nitrogen atoms · CPC title
with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms · CPC title
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- What does patent US10640457B2 cover?
- The invention provides for a method for screening compounds that bind to and modulate a histone acetyltransferase protein. The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a HAT-activating compound to…
- Who is the assignee on this patent?
- Feng Yan, Fa Mauro, Arancio Ottavio, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C07C235/64. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue May 05 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).