Mixing method and system

Patent metadata

Field	Value
Publication number	US-10625210-B2
Application number	US-201615769461-A
Country	US
Kind code	B2
Filing date	Oct 28, 2016
Priority date	Nov 10, 2015
Publication date	Apr 21, 2020
Grant date	Apr 21, 2020

Abstract

A method and a system for improving mixing of content in a container 3 provided in a filter system 1, said method comprising providing a mixing loop 13 parallel to a recirculation flow path 11 of the filter system 1.

First claim

The invention claimed is:

1. A method for improving mixing of content in a container provided in a filter system, said container being connected to a filter by a recirculation flow path, said method comprising providing a mixing loop to the container, said mixing loop being provided in parallel with the recirculation flow path of the filter system, further comprising controlling a mixing pump provided in the mixing loop in dependence of operational conditions of a feed pump arranged to supply content from the container to the filter and further comprising the steps of:
switching the mixing pump on when the feed pump pumps feed to the filter at a flow rate below a predefined threshold rate; and/or
switching the mixing pump off when the feed pump pumps feed to the filter at a flow rate above a predefined threshold rate.

2. The method according to claim 1 , further comprising controlling a mixing pump provided in the mixing loop in dependence of properties of content in the system and/or conditions in the system.

3. A method for improving mixing of content in a container provided in a filter system, said container being connected to a filter by a recirculation flow path, said method comprising providing a mixing loop to the container, said mixing loop being provided in parallel with the recirculation flow path of the filter system, further comprising controlling a mixing pump provided in the mixing loop in dependence of sensor responses from at least two sensors provided at different locations in the system, said sensors measuring the same property of the content in the container.

4. A method for improving mixing of content in a container provided in a filter system, said container being connected to a filter by a recirculation flow path, said method comprising providing a mixing loop to the container, said mixing loop being provided in parallel with the recirculation flow path of the filter system, further comprising controlling a mixing pump provided in the mixing loop in dependence of fluid flow into the container provided from an additional pump and fluid line separate from the recirculation flow path.

5. A filter system comprising a container with a content connected to a filter by a recirculation flow path, wherein the filter system further comprises a mixing loop in connection with the container, said mixing loop being provided in parallel with the recirculation flow path, and further comprising a control system arranged to control a mixing pump provided in the mixing loop in dependence of sensor responses from at least two sensors provided at different locations in the system and measuring the same property of the content in the container.

6. The filter system according to claim 5 , further comprising a control system arranged to control a mixing pump provided in the mixing loop in dependence of properties of content in the system and/or conditions in the system.

7. The filter system according to claim 5 , wherein the control system is further in dependence of operational conditions of a feed pump provided in the recirculation flow path.

8. The filter system according to claim 7 , wherein said filter system comprises the container with a content, the filter connected by the recirculation flow path to a recirculation inlet and a recirculation outlet of the container and a feed pump provided in the recirculation flow path pumping content of the container to the filter, wherein the filter system further comprises the mixing loop parallel to the recirculation flow path, said mixing loop comprising a mixing pump and is connected to a mixing inlet and a mixing outlet of the container and said filter system comprising the control system which can communicate with both the mixing pump and the feed pump.

9. A filter system comprising a container with a content connected to a filter by a recirculation flow path, wherein the filter system further comprises a mixing loop in connection with the container, said mixing loop being provided in parallel with the recirculation flow path,
wherein the filter system further comprises a control system arranged to control a mixing pump provided in the mixing loop in dependence of operational conditions of a feed pump provided in the recirculation flow path and the container with a content, the filter connected by the recirculation flow path to a recirculation inlet and a recirculation outlet of the container and a feed pump provided in the recirculation flow path pumping content of the container to the filter, wherein said mixing loop comprising the mixing pump is connected to a mixing inlet and a mixing outlet of the container, and said filter system comprising the control system can communicate with both the mixing pump and the feed pump; and
wherein the control system further is arranged to control the mixing pump to be switched on when the feed pump pumps feed to the filter at a flow rate below a predefined threshold rate and/or control the mixing pump to be switched off when the feed pump pumps feed to the filter at a flow rate above a predefined threshold rate.

10. The filter system according to claim 5 , wherein the container is a hanging bag.

Assignees

• Ge Healthcare Bio Sciences Ab

Inventors

• Gebauer Klaus
• Doddapadam Srinivasa Raghavachar Partha Sarathy
• G R Narendra
• Karmarkar Nachiket
• Vernekar Ajit S
• Mohan Prashanth Hosabettu
• Nutalapati Sasi Kumar

Classifications

• B01D2315/16

  Diafiltration · CPC title

• B01D61/20 Primary

  Accessories; Auxiliary operations · CPC title

• B01D2313/083

  Bypass routes · CPC title

• B01F5/102

  Operations & Transport · mapped topic

• B01F15/00253

  Operations & Transport · mapped topic