Antiseptic product, process for preparing same and its use

Patent metadata

Field	Value
Publication number	US-10624348-B2
Application number	US-201515325236-A
Country	US
Kind code	B2
Filing date	Aug 5, 2015
Priority date	Aug 7, 2014
Publication date	Apr 21, 2020
Grant date	Apr 21, 2020

Abstract

The present invention relates to a process for preparing an antiseptic product, an antiseptic product obtainable by the process, an antiseptic inorganic powder composition, an antiseptic polymer product as well as the use of one or more source of lithium ions in combination with one or more source of sodium ions for the preparation of an antiseptic product being effective against microbial contamination.

First claim

The invention claimed is:

1. An antiseptic composition comprising:
a) at least one inorganic filler material,
b) one or more source of sodium ions wherein from 20 to 20,000 milligrams per kilogram of the antiseptic composition consists of the source of sodium ions, and
c) one or more source of lithium ions wherein 20 to 60,000 milligrams per kilogram of the antiseptic composition consists of the source of lithium ions,
provided that the antiseptic composition comprises a number of moles of lithium ions from the one or more source of lithium ions per mole of sodium ions from the one or more source of sodium ions and the number is from 5 to 10,
wherein the antiseptic composition comprises <15.0 wt.-% moisture, and
the antiseptic composition is effective against one or more of (i) a strain of bacteria, (ii) a strain of yeast, and (iii) a strain of mould.

2. The antiseptic composition according to claim 1 , wherein the antiseptic composition comprises ≤5.0 wt.-%, moisture.

3. The antiseptic composition according to claim 1 , wherein the antiseptic composition comprises ≤1.0 wt.-% moisture.

4. The antiseptic composition according to claim 1 , wherein the antiseptic composition comprises ≤0.2 wt.-% moisture.

5. The antiseptic composition according to claim 1 , wherein the antiseptic composition comprises from 0.03 to 0.15 wt.-% moisture.

6. The antiseptic composition according to claim 1 , having hydrophobic surface properties.

7. The antiseptic composition according to claim 1 , wherein the at least one inorganic filler material is selected from the group consisting of ground natural calcium carbonate (GCC), precipitated calcium carbonate (PCC), modified calcium carbonate (MCC), kaolin, kaolinitic clay, calcined kaolinitic clay, talc, calcium sulfate, quartz, attapulgite, montmorillonite, diatomaceous earth, finely divided silica, aluminium oxide, aluminium hydroxide, silicates, pumice, sepiolite, dolomite, mica, titanium dioxide, and any mixture thereof.

8. The antiseptic composition according to claim 1 , wherein the at least one inorganic filler material is selected from the group consisting of ground natural calcium carbonate (GCC) from marble, limestone, chalk or any mixture thereof, modified calcium carbonate (MCC), precipitated calcium carbonate (PCC), dolomite, kaolin, kaolinitic clay, calcined kaolinitic clay, and any mixture thereof.

9. The antiseptic composition according to claim 1 , wherein the at least one inorganic filler material is ground natural calcium carbonate (GCC).

10. The antiseptic composition according to claim 1 , wherein the at least one inorganic filler material has a volume median diameter d 50 value from 0.5 to 25.0 μm, measured according to the dry laser diffraction method.

11. The antiseptic composition according to claim 1 , wherein the at least one inorganic filler material has a volume median diameter d 50 value from 0.7 to 5.0 μm, measured according to the dry laser diffraction method.

12. The antiseptic composition according to claim 1 , comprising from 20 to 10,000 milligrams of sodium ions per kilogram of the antiseptic composition.

13. The antiseptic composition according to claim 1 , comprising from 20 to 30,000 milligrams of lithium ions per kilogram of the antiseptic composition.

14. The antiseptic composition according to claim 1 , wherein the one or more source of sodium ions is a carbonate salt, the one or more source of lithium ions is a carbonate salt, or the one or more source of sodium ions is a carbonate salt and the one or more source of lithium ions is a carbonate salt.

15. The antiseptic composition according to claim 1 , wherein the antiseptic composition does not comprise any additional biocide.

16. The antiseptic composition according to claim 1 , which is prepared by a process comprising the steps of:
a) providing the at least one inorganic filler material,
b) providing the one or more source of lithium ions,
c) providing the one or more source of sodium ions,
d) combining the at least one inorganic filler material with the one or more source of lithium ions, and
e) combining the at least one inorganic filler material with the one or more source of sodium ions, wherein
process steps d) and e) are carried out simultaneously or separately in any order, provided that the antiseptic composition comprises a number of moles of lithium ions from the source of lithium ions per mole of sodium ions from the source of sodium ions and the number is from 1.5 to 10, and
the antiseptic composition comprises <15.0 wt.-% moisture.

17. The antiseptic composition according to claim 16 , wherein the process further comprises step f) of:
i) dry grinding the mixture of the at least one inorganic filler material, the one or more source of lithium ions and the one or more source of sodium ions obtained during and/or after step d) and e), and/or
ii) contacting the mixture of the at least one inorganic filler material, the one or more source of lithium ions and the one or more source of sodium ions obtained after step d) and e) with water and/or at least one dispersing agent, or
iii) contacting the mixture of the at least one inorganic filler material, the one or more source of lithium ions and the one or more source of sodium ions obtained after step d) and e) with an organic polymer composition comprising at least one organic polymer resin being selected from the group consisting of a thermoplast, duroplast, elastomer and mixtures thereof and subjecting the obtained composition to conditions under which it is converted into an antiseptic polymer product.

18. The antiseptic composition according to claim 1 , wherein the strain of bacteria is selected from the group consisting of Escherichia sp., Staphylococcus sp., Thermus sp., Propionibacterium sp., Rhodococcus sp., Panninobacter sp., Caulobacter sp., Brevundimonas sp., Asticcacaulis sp., Sphingomonas sp., Rhizobium sp., Ensifer sp., Bradyrhizobium sp., Tepidimonas sp., Tepidicella sp., Aquabacterium sp., Pelomonas sp., Alcaligenis sp., Achromobacter sp., Ralstonia sp., Limnobacter sp., Massilia sp., Hydrogenophaga sp., Acidovorax sp., Curvibacter sp., Delftia sp., Rhodoferax sp., Alishewanella sp., Stenotrophomonas sp., Dokdonella sp., Methylosinus sp., Hyphomicrobium sp., Methylosulfomonas sp., Methylobacteria sp., Pseudomonas sp. Enterococcus sp., Myroides sp., Burkholderia sp., Alcaligenes sp., and any mixture thereof, the strain of mould is selected from the group consisting of Acremonium sp., Alternaria sp., Aspergillus sp., Cladosporium sp., Fusarium sp., Mucor sp., Penicillium sp., Rhizopus sp., Stachybotrys sp., Trichoderma sp., Dematiaceae sp., Phoma sp., Eurotium sp., Scopulariopsis sp., Aureobasidium sp., Monilia sp., Botrytis sp., Stemphylium sp., Chaetomium sp., Mycelia sp., Neurospora sp., Ulocladium sp., Paecilomyces sp., Wallemia sp., Curvularia sp., and any mixture thereof, and the strain of yeast is selected from the group consisting of Saccharomycotina, Taphrinomycotina, Schizosaccharomycetes, Basidiomycota, Agaricomycotina, Tremellomycetes, Pucciniomycotina, Microbotryomycetes, Candida sp. such as Candida albicans, Candida tropicalis, Candida stellatoidea, Candida glabrata, Candida krusei, Candida guilliermondii, Candida viswanathii, Candida lusitaniae and mixtures thereof, Yarrowia sp. such as Yarrowia lipolytica, Cryptococcus sp. such as Cryptococcus gattii and Cryptococcus neofarmans, Zygosaccharomyces sp.

Assignees

• Omya Int Ag
• Omya Int

Inventors

• Gane Patrick A C
• Buri Matthias
• Urwyler Simon
• Zumsteg Anita
• Glaubitz Joachim

Classifications

• A01N59/08 Primary

  Alkali metal chlorides; Alkaline earth metal chlorides · CPC title

• C09D5/1618

  inorganic · CPC title

• A01N59/06

  Aluminium; Calcium; Magnesium; Compounds thereof · CPC title

• C08K3/015

  Biocides (macromolecular substances as carriers for biocide material A01N25/10) · CPC title

• C09D5/14

  Paints containing biocides, e.g. fungicides, insecticides or pesticides (C09D5/16 takes precedence) · CPC title