Systems and methods for predicting and controlling the properties of a chemical species during a time-dependent process

Patent metadata

Field	Value
Publication number	US-10620127-B2
Application number	US-201916254532-A
Country	US
Kind code	B2
Filing date	Jan 22, 2019
Priority date	Jan 22, 2015
Publication date	Apr 14, 2020
Grant date	Apr 14, 2020

Abstract

Devices and methods for controlling the properties of chemical species during time-dependent processes. A device includes a reactor for containing one or more chemical species of a time-dependent process, an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor, one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval, and a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point.

First claim

What is claimed is:

1. A method comprising:
introducing, in a reactor, one or more chemical species to be monitored during a time-dependent process;
detecting, using one or more detectors, one or more property changes to the one or more chemical species over a time interval;
receiving, from the one or more detectors, a continuous stream of data related to the one or more property changes to the one or more chemical species during the time interval;
fitting, using a process controller, the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point;
predicting a time period required for a residual chemical species concentration to reach one or more specified levels; and
making, by the process controller, one or more process decisions based on the prediction of one or more properties at the future time point;
wherein the continuous stream of data comprises one or more of UV absorption, visible absorption, infra-red absorption, Raman scattering, fluorescence, reduced viscosity, intrinsic viscosity, dynamic light scattering, static light scattering, Mie scattering, and evaporative light scattering.

2. The method of claim 1 , wherein the one or more process decisions comprise any one of terminating of the time-dependent process, recovering the reactor contents, proceeding to a subsequent reaction or processing stage in the same or a different reactor.

3. The method of claim 1 , wherein the one or more property changes comprises a change in residual monomer concentrations.

4. The method of claim 1 , further comprising fitting the continuous stream of data to a function to predict a grade changeover between a first polymerization reaction product and a second polymerization reaction product of the polymerization reaction, wherein the time-dependent process is a polymerization reaction, and wherein
one of the one or more detectors is a viscometer; and
the predicted grade changeover is derived from reduced viscosity measurements detected by the viscometer during the time interval.

5. The method of claim 4 , wherein the predicted grade changeover is derived from reduced viscosity measurements and correlated to offline Mooney Viscosity measurements.

6. The method of claim 5 , wherein the one or more property changes comprises changes in viscosity of a polymer product formed during the polymerization reaction.

7. The method of claim 5 , wherein the one or more property changes comprises changes in molecular weight of a polymer product formed during the polymerization reaction.

8. The method of claim 1 , further comprising:
changing, using the process controller, one or more conditions of the time-dependent process to alter the predicted one or more properties of the chemical species at the future time point, wherein the one or more conditions comprise any one of reactor pressure, reactor temperature, reaction stir rate, reaction agitation rate, reactant concentration, reagent concentration, or reagent flow rate into the reactor.

9. The method of claim 1 , wherein the one or more property changes comprise changes in any one of concentration, residual monomer concentration, molecular weight, polydispersity, reduced viscosity, intrinsic viscosity, and chemical composition of the one or more chemical species.

10. The method of claim 1 , further comprising:
changing, using the process controller, one or more conditions of the time-dependent process to alter the predicted residual chemical species concentration at a future time point.

11. The method of claim 1 , wherein the method is performed using an Automatic Continuous Online Monitoring of Polymerization reactions (ACOMP) system, the ACOMP system comprising the reactor, the one or more detectors and the process controller.

12. A device comprising:
a reactor for containing one or more chemical species of a time-dependent process;
an extraction pump for automatically and continuously extracting an amount of the one or more chemical species from the reactor;
one or more detectors for measuring property changes of the one or more extracted chemical species and generating a continuous stream of data related to the one or more property changes to the one or more chemical species during a time interval; and
a process controller configured to fit the continuous stream of data to a mathematical function to predict one or more properties of the one or more chemical species at a future time point and make one or more process decisions based on the prediction of one or more properties at the future time point;
wherein the one or more detectors is configured to measure one or more of UV absorption, visible absorption, infra-red absorption, Raman scattering, fluorescence, reduced viscosity, intrinsic viscosity, dynamic light scattering, static light scattering, Mie scattering, and evaporative light scattering.

13. The device of claim 12 , wherein the one or more process decisions comprise any one of terminating of the time-dependent process, recovering the reactor contents, proceeding to a subsequent reaction or processing stage in the same or a different reactor.

14. The device of claim 12 , wherein the process controller is further configured to direct a change in one or more conditions of the time-dependent process to alter the predicted one or more properties of the chemical species at the future time point.

15. The device of claim 14 , wherein the one or more conditions comprise any one of reactor pressure, reactor temperature, reaction stir rate, reaction agitation rate, reactant concentration, reagent concentration, or reagent flow rate.

16. The device of claim 12 , wherein the one or more property changes comprises changes in concentration of the one or more chemical species.

17. The device of claim 12 , wherein the one or more property changes comprises changes in molecular weight of the one or more chemical species.

18. The device of claim 12 , wherein the one or more property changes comprises a change in residual monomer concentration.

19. The device of claim 12 , wherein one or more of the reactor, the extraction pump, the one or more detectors, and the process controller are incorporated in an automatic continuous online monitoring of polymerization (ACOMP) system.

20. The device of claim 12 , further comprising a means of diluting and/or conditioning the one or more extracted contents.

21. The device of claim 20 , wherein one or more of the reactor, the extraction pump, the one or more detectors, the process controller and the means of diluting and/or conditioning are incorporated in an automatic continuous online monitoring of polymerization (ACOMP) system.

22. A method comprising:
introducing, in a reactor, one or more chemical species to be monitored during a time-dependent process;
detecting, using one or more detectors, one or more property changes to the one or more chemical species over a time interval;
receiving, from the one or more detectors, a continuous stream of data related to the one or more property changes to the one or more chemical species during the time interval;
fitting, using a process controller, the continuous stream of data to a mathematical function to predict a grade changeover between a first polymerization reaction product and a second polymerization reaction product of the polymerization reaction, wherein the time-dependent process is a polymerization reaction, wherein
one of the one or more detectors is a v

Assignees

• Advanced Polymer Monitoring Tech Inc
• The Administrators Of The Tulane Educational Fund

Inventors

• Reed Wayne Frederick
• Drenski Michael Felix

Classifications

• B01J2219/00063

  of the reactants · CPC title

• B01J2208/00637

  Means for stopping or slowing down the reaction · CPC title

• B01J2208/00061

  of the reactants · CPC title

• B01J2208/00548

  Flow · CPC title

• B01J2219/00218

  Dynamically variable (in-line) parameter values · CPC title