Determining fluid reservoir connectivity using nanowire probes

Patent metadata

Field	Value
Publication number	US-10620107-B2
Application number	US-201515308049-A
Country	US
Kind code	B2
Filing date	May 5, 2015
Priority date	May 5, 2014
Publication date	Apr 14, 2020
Grant date	Apr 14, 2020

Abstract

Systems and methods of fabricating and functionality patterned nanowire probes that are stable under fluid reservoir conditions and have imageable contrast are provided. Optical imaging and deconstruction methods and systems are also provided that are capable of determining the distribution of nanowires of a particular pattern to determine the mixing between or leakage from fluid reservoirs.

First claim

What is claimed is:

1. A method of determining reservoir flow comprising:
introducing at least one probe population formed of a plurality of nanowires into a fluid medium in at least one fluid reservoir such that a mixture of nanowires and fluid medium is formed within the at least one fluid reservoir, the probe population having a distinct imageable pattern associated therewith, wherein the distinct imageable pattern associated with the population being formed on each of the plurality of nanowires of said population;
obtaining a sample of the mixture from at least one of the at least one fluid reservoir;
optically imaging the sample; and
processing the imaged sample using a signal processor to identify the at least one probe population disposed within the sample, wherein the identification of the at least one probe population indicates a flow from the at least one fluid reservoir, and wherein the signal processor is programmed with an automated algorithm and capable of differentiating the distinct imageable patterns associated with each population of nanowires.

2. The method of claim 1 , comprising:
introducing at least two probe populations each formed of a plurality of nanowires into a plurality of fluid reservoirs,
wherein each of the at least two probe populations is introduced into a separate fluid reservoir in the plurality of fluid reservoirs such that a mixture of nanowires and fluid medium is formed within each fluid reservoir in the plurality of fluid reservoirs,
wherein each population of nanowires having a distinct imageable pattern associated therewith, the distinct imageable pattern associated with the population being formed on each of the plurality of nanowires of said population;

obtaining a sample of the mixture within each of the plurality of fluid reservoirs;
imaging the samples from each of the plurality of fluid reservoirs; and
processing the imaged samples using a signal processor to identify each of the at least two probe populations disposed within the samples, wherein the identification of each of the at least two probe populations indicates a flow from the fluid reservoir in which each of the at least two probe populations was introduced, and wherein the signal processor is programmed with an automated algorithm and capable of differentiating the distinct imageable patterns associated with each population of nanowires.

3. The method of claim 1 , wherein the nanowires are comprised of a plurality of segments disposed adjacent each other along the longitudinal axis of the nanowire.

4. The method of claim 1 , wherein the imageable pattern is optically imageable and wherein the imaging comprises a video imagery technique selected from the group consisting of computer vision and wavelet-based image processing.

5. The method of claim 1 , wherein the processing comprises automatically sorting the images from the sample by a processing technique selected from the group consisting of wavelet Gizburg-Landau regularization, spectral analysis of large Hermitian matrices, and modularity optimization.

6. The method of claim 1 , further comprising deconstructing and or reconstructing the imaged mixture sample using an image processing technique selected from the group consisting of total variation restoration, cartoon texture decomposition, and nonlocal TV reconstruction.

7. The method of claim 1 , wherein the sampling and imaging occurs within the flow from the at least one fluid reservoir.

8. The method of claim 1 , wherein the plurality of nanowires in each population are formed of at least two sizes.

9. The method of claim 8 , wherein at least two of the segments are formed from different materials having an imageable contrast therebetween, the imageable contrast between the different segments forming the imageable pattern.

10. The method of claim 1 , wherein the outer surface of each of the nanowires is functionalized with a plurality of functional groups configured to prevent agglomeration of the nanowires.

11. The method of claim 10 , wherein the plurality of functional groups do not obscure the imageable pattern.

12. The method claim 1 , wherein an encapsulation layer is disposed on the outer surface of each of the nanowires.

13. The method of claim 12 , wherein the encapsulation layer is functionalized with a plurality of functional groups configured to prevent agglomeration of the nanowires.

14. The method of claim 13 , wherein the encapsulation layer and the plurality of functional groups do not obscure the imageable pattern.

Assignees

• Univ California

Inventors

• Weiss Paul S
• Andrews Anne M
• Bertozzi Andrea L
• Osher Stanley J

Classifications

• G01N2015/1486

  Counting the particles · CPC title

• G01N15/0806 Primary

  Details, e.g. sample holders, mounting samples for testing · CPC title

• G01M3/226

  for containers, e.g. radiators · CPC title

• G01N2015/0038

  Investigating nanoparticles · CPC title

• G01N15/06 Primary

  Investigating concentration of particle suspensions (by weighing G01N5/00; investigating sedimentation of particle suspensions G01N15/04; investigating individual particles G01N15/10) · CPC title