Aerosol delivery system with humidification
US-2017182266-A1 · Jun 29, 2017 · US
US10617840B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10617840-B2 |
| Application number | US-201515301318-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 10, 2015 |
| Priority date | Apr 11, 2014 |
| Publication date | Apr 14, 2020 |
| Grant date | Apr 14, 2020 |
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Official abstract text for this publication.
A high flow nasal therapy system ( 1 ) has a gas supply ( 2 ), a nebulizer ( 12 ), and a nasal interface ( 7 ). There are two branches ( 11, 10 ) and a valve ( 6 ) linked with the controller, the branches including a first branch ( 11 ) for delivery of aerosol and a second branch ( 10 ) for delivery of non-aerosolized gas. The controller controls delivery into the branches ( 11, 10 ), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch ( 11 ) includes the nebulizer ( 12 ) and a line configured to store a bolus of aerosol during flow through the second branch ( 10 ). The valve ( 6 ) comprises a Y-junction between the gas inlet on one side and the branches on the other side.
Opening claim text (preview).
The invention claimed is: 1. A high flow nasal therapy system comprising: a gas supply, a humidifier, a nebulizer, a flow line, a nasal interface, and a controller configured to control the system in real time to vary aerosol delivery to the nasal interface on a temporal basis, wherein the controller is configured to provide an increased aerosol delivery during patient inhalation and a reduced aerosol delivery during patient exhalation, wherein the controller is configured to temporarily reduce a gas flow rate in the flow line and to the nebulizer, the reduced gas flow rate being maintained for the duration of active aerosol generation, and increase the gas flow rate in the flow line at end of dose. 2. A high flow nasal therapy system as claimed in claim 1 , wherein the system comprises at least two branches and a valve linked with the controller, the at least two branches including a first branch for delivery of aerosol and a second branch for delivery of non-aerosolized gas, and wherein the controller is configured to control delivery into the first branch and the second branch, in which flow is unidirectional in the first branch and the second branch from the gas supply towards the nasal interface. 3. A high flow nasal therapy system as claimed in claim 2 , wherein the first branch includes the nebulizer. 4. A high flow nasal therapy system as claimed in claim 2 , wherein the first branch includes a line configured to store a bolus of aerosol during flow through the second branch. 5. A high flow nasal therapy system as claimed in claim 2 , wherein the valve comprises a Y-junction between a gas inlet on one side and the first branch and the second branch on the other side. 6. A high flow nasal therapy system as claimed in claim 2 , wherein the valve is configured to perform splitting of inlet gas flow between the first branch and the second branch with a desired proportional split set according to the controller. 7. A high flow nasal therapy system as claimed in claim 2 , wherein the first branch has a larger cross-sectional area than the second branch. 8. A high flow nasal therapy system as claimed in claim 2 , wherein one or both of the branches comprises a heater. 9. A high flow nasal therapy system as claimed in claim 2 , wherein the first branch and the second branch join at a common conduit, and said common conduit being in turn linked with said nasal interface. 10. A high flow nasal therapy system as claimed in claim 2 , wherein the humidifier is included in the second branch. 11. A high flow nasal therapy system as claimed in claim 10 , wherein the first branch comprises a heater, and the controller is configured to control said heater to provide the first branch with an elevated temperature compared to the second branch. 12. A high flow nasal therapy system as claimed in claim 10 , wherein the first branch includes a restrictor for causing more restricted flow through said first branch than through the second branch. 13. A high flow nasal therapy system as claimed in claim 1 , wherein the controller is configured to increase the gas flow rate in the flow line during inactive aerosol generation. 14. A high flow nasal therapy system, comprising: a gas supply; a humidifier; a nebulizer; a flow line; a sensor for detecting flow conditions; at least one of a nasal interface or a coupler for connection to an external interface; and a controller configured to: control the system in real time to vary aerosol delivery to the at least one of the nasal interface or the coupler on a temporal basis; vary aerosol output of the nebulizer at least partly in response to a detected flow condition sensed by the sensor; and temporarily reduce a gas flow rate in the flow line for the duration of active aerosol generation, and increase a gas flow rate in the flow line at end of dose. 15. A high flow nasal therapy system as claimed in claim 14 , wherein the sensor is at least one of a flow meter or pressure transducer. 16. A high flow nasal therapy system as claimed in claim 14 , wherein the sensor is positioned downstream of the nebulizer. 17. A high flow nasal therapy system, comprising: a gas supply; a humidifier; a nebulizer; a flow line; at least one of a nasal interface or a coupler for connection to an external interface; and a controller configured to: control the system in real time to vary aerosol delivery to the at least one of the nasal interface or the coupler on a temporal basis, temporarily reduce gas flow rate in said flow line for the duration of active aerosol generation, and increase gas flow rate in said flow line at end of dose. 18. A high flow nasal therapy system as claimed in claim 17 , wherein the controller is configured to vary aerosol output so as to turn on or turn off aerosol output. 19. A high flow nasal therapy system as claimed in claim 17 , wherein the controller is configured to control aerosol delivery at least partly according to a configured control scheme. 20. A high flow nasal therapy system as claimed in claim 19 , wherein the configured control scheme is set according to dosage requirements.
Nasal cannulas or tubing (devices for improving normal breathing through the nose A61F5/08; nose filters A62B23/06; outside holding devices A61M25/02) · CPC title
Sprayers or atomisers specially adapted for therapeutic purposes (in general B05B; {aerosol containers B65D83/14}) · CPC title
Devices to humidify the respiration air {(A61M16/1045 takes precedence)} · CPC title
Inhaling devices inserted into the nose · CPC title
by mixing different fluids, one of them being in a liquid phase · CPC title
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