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US-9802899-B2 · Oct 31, 2017 · US
Process for the preparation of triazoles
US10611734B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10611734-B2 |
| Application number | US-201615552782-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 19, 2016 |
| Priority date | Feb 24, 2015 |
| Publication date | Apr 7, 2020 |
| Grant date | Apr 7, 2020 |
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- Title
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- Abstract
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Abstract
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The present invention discloses the efficient preparation of 2-substituted-4-amido-1,2,3-triazoles.
First claim
Opening claim text (preview).
The invention claimed is: 1. A process for preparation of one or more compounds of formula 1 wherein R 2 is an alkyl, aromatic, or heterocyclic group, R 3 is phenyl substituted at 2- and 6-positions with substituents independently selected from the group consisting of C 1-4 alkyl, C 1-4 haloalkyl, C 1-4 alkoxy, nitro, nitrile, and halogen, by conversion of one or more compounds of formula 4 in which R 2 and R 3 have the above mentioned meanings, into one or more compounds of formula 1, wherein the conversion is effected in the presence of an activating agent, and wherein the activating agent is selected from the group consisting of NaOH, HCl, Cu(OAc) 2 , and MeSO 3 H. 2. The process according to claim 1 , wherein R 2 is 2-CF 3 Ph, and R 3 is 2,6-F 2 Ph. 3. The process according to claim 1 , wherein R 3 is phenyl independently substituted at 2- and 6-positions with halogen. 4. The process according to claim 1 , wherein R 3 is 2,6-F 2 Ph. 5. The process according to claim 1 , wherein R 2 is an aromatic group. 6. The process according to claim 1 , wherein R 2 is 2-CF 3 Ph. 7. The process according to claim 1 , wherein the activating agent is NaOH. 8. The process according to claim 1 , wherein the activating agent is HCl. 9. The process according to claim 1 , wherein the activating agent is Cu(OAc) 2 . 10. The process according to claim 1 , wherein the activating agent is MeSO 3 H.
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Classifications
directly linked by a ring-member-to-ring-member bond · CPC title
linked by a chain containing hetero atoms as chain links · CPC title
- C07C259/14Primary
having carbon atoms of hydroxamidine groups bound to hydrogen atoms or to acyclic carbon atoms · CPC title
1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles · CPC title
- C07D401/04Primary
directly linked by a ring-member-to-ring-member bond · CPC title
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Frequently asked questions
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- What does patent US10611734B2 cover?
- The present invention discloses the efficient preparation of 2-substituted-4-amido-1,2,3-triazoles.
- Who is the assignee on this patent?
- Bayer Cropscience Ag
- What technology area does this patent fall under?
- Primary CPC classification C07C259/14. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Apr 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 3 related publications on this page (citations in our corpus or others sharing the same primary CPC).