Methods of preventing secondary infections

US10610588B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10610588-B2
Application numberUS-201615549161-A
CountryUS
Kind codeB2
Filing dateFeb 9, 2016
Priority dateFeb 9, 2015
Publication dateApr 7, 2020
Grant dateApr 7, 2020

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  4. Key dates

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  5. First independent claim

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  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

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Abstract

Official abstract text for this publication.

A method of treating or preventing a disease associated with a secondary infection in a subject infected with a pathogen is provided. The method comprises administering to the subject a therapeutically effective amount of an anti-pathogenic agent directed towards the pathogen and a therapeutically effective amount of an agent which down-regulates at least one extracellular matrix-associated polypeptide.

First claim

Opening claim text (preview).

What is claimed is: 1. A method of treating a subject infected with a pathogen comprising administering to the subject a therapeutically effective amount of an anti-pathogenic agent directed towards said pathogen and a therapeutically effective amount of an agent which specifically down-regulates membrane type 1-matrix metalloproteinase 1 (MT1-MMP1), thereby treating the subject. 2. A method of treating influenza in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an agent which specifically down-regulates MT1-MMP1. 3. The method of claim 2 , wherein the administering is effected no more than 2 days after the start of symptoms of the infection. 4. The method of claim 1 , wherein said agent which specifically down-regulates MT1-MMP1 is an antibody.

Assignees

Inventors

Classifications

  • against enzymes · CPC title

  • against proteinaceous materials, e.g. enzymes, hormones, lymphokines · CPC title

  • not condensed with another ring · CPC title

  • Drugs for disorders of the respiratory system · CPC title

  • comprising antibodies · CPC title

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Frequently asked questions

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What does patent US10610588B2 cover?
A method of treating or preventing a disease associated with a secondary infection in a subject infected with a pathogen is provided. The method comprises administering to the subject a therapeutically effective amount of an anti-pathogenic agent directed towards the pathogen and a therapeutically effective amount of an agent which down-regulates at least one extracellular matrix-associated pol…
Who is the assignee on this patent?
Yeda Res & Dev
What technology area does this patent fall under?
Primary CPC classification A61K39/3955. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Apr 07 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).