Methods and compositions for treating melanoma
US-2024424002-A1 · Dec 26, 2024 · US
US10610588B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10610588-B2 |
| Application number | US-201615549161-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 9, 2016 |
| Priority date | Feb 9, 2015 |
| Publication date | Apr 7, 2020 |
| Grant date | Apr 7, 2020 |
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A method of treating or preventing a disease associated with a secondary infection in a subject infected with a pathogen is provided. The method comprises administering to the subject a therapeutically effective amount of an anti-pathogenic agent directed towards the pathogen and a therapeutically effective amount of an agent which down-regulates at least one extracellular matrix-associated polypeptide.
Opening claim text (preview).
What is claimed is: 1. A method of treating a subject infected with a pathogen comprising administering to the subject a therapeutically effective amount of an anti-pathogenic agent directed towards said pathogen and a therapeutically effective amount of an agent which specifically down-regulates membrane type 1-matrix metalloproteinase 1 (MT1-MMP1), thereby treating the subject. 2. A method of treating influenza in a subject in need thereof comprising administering to the subject a therapeutically effective amount of an agent which specifically down-regulates MT1-MMP1. 3. The method of claim 2 , wherein the administering is effected no more than 2 days after the start of symptoms of the infection. 4. The method of claim 1 , wherein said agent which specifically down-regulates MT1-MMP1 is an antibody.
against enzymes · CPC title
against proteinaceous materials, e.g. enzymes, hormones, lymphokines · CPC title
not condensed with another ring · CPC title
Drugs for disorders of the respiratory system · CPC title
comprising antibodies · CPC title
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