Process for the preparation of a particulate dental filler composition

Patent metadata

Field	Value
Publication number	US-10610459-B2
Application number	US-201615548227-A
Country	US
Kind code	B2
Filing date	Feb 4, 2016
Priority date	Feb 5, 2015
Publication date	Apr 7, 2020
Grant date	Apr 7, 2020

Abstract

Process for the preparation of a particulate dental filler composition, comprising the following steps: (a) introducing a mixture containing (a1) a silica precursor component, and (a2) a solution or dispersion of one or more compounds selected from compounds of aluminum, zinc, titanium, zirconium, tungsten, ytterbium, hafnium, bismuth, barium, strontium, silver, tantalum, lanthanum, tin, boron, and cerium, into a pulsed reactor; (b) converting the silica precursor component and the compounds into a particulate mixed oxide with a pulsed gas flow resulting from flameless combustion; (c) isolating the particulate mixed oxide from the pulsed reactor; (d) optionally subjecting the particulate mixed oxide to a heat treatment step; and (e) treating the optionally heat-treated particulate mixed oxide with a silane treatment agent for obtaining a particulate dental filler composition.

First claim

The invention claimed is:

1. Process for preparation of a particulate dental filler composition, comprising steps of:
(a) introducing a mixture containing
(a1) a silica precursor component, and
(a2) a solution or dispersion of one or more compounds of aluminum, zinc, titanium, zirconium, tungsten, ytterbium, hafnium, bismuth, barium, strontium, silver, tantalum, lanthanum, tin, boron, or cerium,
into a pulsed reactor;

(b) converting the silica precursor component and the one or more compounds into a particulate mixed oxide with a pulsed gas flow resulting from flameless combustion; wherein the formation of the particulate mixed oxide is carried out in a single step in the pulse reactor;
(c) isolating the particulate mixed oxide from the pulsed reactor;
(d) optionally subjecting the particulate mixed oxide to a heat treatment step; and
(e) treating the particulate mixed oxide or heat-treated particulate mixed oxide with a silane treatment agent for obtaining a particulate dental filler composition;
wherein the silane treatment agent contains one or more silane compounds capable of forming a covalent bond between the surface atoms of the particulate mixed oxide and the one or more silane compounds, and the one or more silane compounds contain one or more polymerizable double bonds reactive in a crosslinking reaction after the particulate dental filler composition is incorporated in a polymerizable dental restorative composition.

2. The process according to claim 1 , wherein the one or more compound contains one or more elements selected from aluminum, zinc, titanium, zirconium, tungsten, ytterbium, hafnium, barium, and strontium.

3. The process according to claim 1 , wherein the step of converting the silica precursor component and the compounds into a particulate mixed oxide with a pulsed gas flow resulting from flameless combustion further comprises forming a coating on the outer surface of the particulate mixed oxide.

4. The process according to claim 3 , wherein the coating contains an oxide, nitride, a carbide, a silicide, a boride or a fluoride of a metal, a metalloid and/or a lanthanoid.

5. Process for a preparation of a dental restorative material comprising steps of:
(i) providing a dental filler composition obtained according to a process comprising steps of:
(a) introducing a mixture containing
(a1) a silica precursor component, and
(a2) a solution or dispersion of one or more compounds of aluminum, zinc, titanium, zirconium, tungsten, ytterbium, hafnium, bismuth, barium, strontium, silver, tantalum, lanthanum, tin, boron, or cerium,
into a pulsed reactor;

(b) converting the silica precursor component and the one or more compounds into a particulate mixed oxide with a pulsed gas flow resulting from flameless combustion; wherein the formation of the particulate mixed oxide is carried out in a single step in the pulse reactor;
(c) isolating the particulate mixed oxide from the pulsed reactor;
(d) optionally subjecting the particulate mixed oxide to a heat treatment step; and
(e) treating the particulate mixed oxide or heat-treated particulate mixed oxide with a silane treatment agent for obtaining a particulate dental filler composition;
wherein the silane treatment agent contains one or more silane compounds capable of forming a covalent bond between the surface atoms of the particulate mixed oxide and the one or more silane compounds, and the one or more silane compounds contain one or more polymerizable double bonds reactive in a crosslinking reaction after the particulate dental filler composition is incorporated in a polymerizable dental restorative composition;

(ii) providing one or more polymerizable compounds and/or one or more polymers; and optionally
(iii) providing a polymerization initiator system; and
(iv) incorporating the dental filler composition into a dental resin matrix.

Assignees

• Dentsply Sirona Inc

Inventors

• Uwe Walz
• Weber Christoph
• Maximillian Maier

Classifications

• A61K6/82

  comprising hafnium oxide · CPC title

• A61K6/818

  comprising zirconium oxide · CPC title

• A61K6/76 Primary

  comprising silicon-containing compounds · CPC title

• C01B13/20 Primary

  by oxidation of elements in the gaseous state; by oxidation or hydrolysis of compounds in the gaseous state · CPC title

• C01B33/20

  Silicates (persilicates C01B15/14 {; containing aluminium C01B33/26}) · CPC title