Textile engineered prosthetics, bioreactors, and methods of manufacturing textile engineered prosthetics

Patent metadata

Field	Value
Publication number	US-10610347-B2
Application number	US-201615074141-A
Country	US
Kind code	B2
Filing date	Mar 18, 2016
Priority date	Mar 19, 2015
Publication date	Apr 7, 2020
Grant date	Apr 7, 2020

Abstract

A textile engineered prosthetic includes a continuous tube and at least one band of increased thickness formed over a portion of the continuous tube. The continuous tube includes a body portion and a bifurcated portion. The band of increased thickness forms a biomimetic surface. A bioreactor system includes a bioreactor container including a first compartment, a second compartment, a first membrane separating the first and second compartments, a third compartment, and a second membrane separating the second and third compartments. The bioreactor system also includes a woven textile prosthetic integrated with the bioreactor container in the second compartment to form a single bioreactor unit. A furcated textile article includes a continuous tube having a body portion and a furcated portion bifurcated N times from the body portion. The furcated textile article is a continuous woven piece formed from N shuttles of a shuttle loom, where N is at least two.

First claim

What is claimed is:

1. A method of manufacturing a furcated textile article comprising:
weaving a continuous tube with a shuttle loom;
furcating the continuous tube into N portions, wherein N is at least two, where N is equal to a shuttle capacity of the shuttle loom;
forming at least one band of increased thickness formed over a portion of the continuous tube, wherein the at least one band of increased thickness forms a biomimetic surface; and
wherein the band is C-shaped.

2. The method of claim 1 , where N is at least three.

3. The method of claim 1 , where N is at least four.

4. The method of claim 1 , wherein the furcated textile article is a vascular graft.

5. The method of claim 1 , wherein weaving the continuous tube comprises forming a body portion and a bifurcated portion extending from the body portion.

6. The method of claim 1 , wherein forming the band includes a six-step shuttle sequence comprising:
(1) moving from face of the fabric left to face of the fabric right to weave a face of the fabric;
(2) moving from face of the fabric right to back of the fabric left to weave a back fabric right;
(3) moving from back of the fabric left to back of the fabric right to weave the back fabric right;
(4) moving from back of the fabric right to face of the fabric left to weave the face of the fabric;
(5) moving from face of the fabric left to back of the fabric right to weave a back fabric left; and
(6) moving from back of the fabric right to back of the fabric left to weave the back fabric left.

7. The method of claim 1 , wherein forming the band includes a four-step shuttle sequence comprising:
(1) moving from face of the fabric left to face of the fabric right to weave a face of the fabric;
(2) moving from face of the fabric right to face of the fabric left to weave the face of the fabric;
(3) moving from face of the fabric left to back of the fabric right to weave a back of the fabric; and
(4) moving from back of the fabric right to back of the fabric left to weave the back of the fabric.

8. The method of claim 1 , wherein the textile engineered prosthetic comprises a prosthetic trachea.

9. The method of claim 1 , wherein the band extends around ⅓ to ⅔ of an outer diameter of the continuous tube.

10. The furcated textile article of claim 1 , wherein the furcated textile article is a prosthetic trachea.

11. The method of claim 1 , wherein the at least one band of increased thickness is integral to the continuous tube.

12. The method of claim 9 , wherein the at least one band of increased thickness is integral to the continuous tube.

13. The method of claim 1 , wherein the thickness is measured in a radial direction of the continuous tube.

Assignees

• Secant Group Llc

Inventors

• Whiting Eric H
• Winner Seth A
• Ho Emily Y
• Gabriele Peter
• Harris Jeremy J

Classifications

• A61F2/04 Primary

  Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts (A61F2/18, A61F2/20 take precedence; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95) · CPC title

• D10B2509/06

  Vascular grafts; stents · CPC title

• A61F2002/046

  Tracheae · CPC title

• A61F2240/001

  Designing or manufacturing processes · CPC title

• A61F2250/0036

  differing in thickness · CPC title