Microneedle

Patent metadata

Field	Value
Publication number	US-10603476-B2
Application number	US-201715673739-A
Country	US
Kind code	B2
Filing date	Aug 10, 2017
Priority date	Feb 16, 2015
Publication date	Mar 31, 2020
Grant date	Mar 31, 2020

Abstract

A microneedle including a projection having a through hole formed in the projection in a direction that the projection extends, and a tubular member having an end surface configured to support the projection when the end surface is pressed against a skin and a fluid is supplied through the through hole of the projection to the skin. The projection has a length H along the direction that the projection extends and the supporting surface has an area S such that a ratio of S/H is in a range of from 2.1 to 10.5.

First claim

What is claimed is:

1. A microneedle, comprising:
a projection having a through hole such that the through hole is formed to extend in a first direction that the projection extends; and
a tubular member configured to supply a fluid to the through hole of the projection and having an end surface such that the projection is formed on the end surface of the tubular member and that the end surface has a support surface configured to be pressed against a skin when the projection injects the fluid through the through hole to the skin,
wherein the projection is continuously tapered and has a length H has a length H extending from the support surface of the tubular member at one end to a tip end of the projection at an opposite end of the projection along the first direction perpendicular to the support surface of the tubular member, and the supporting surface at the end surface of the tubular member has an area S such that a ratio of S/H is in a range from 2.1 to 10.5.

2. The microneedle of claim 1 , wherein the tubular member has the end surface at a distal end and a proximal end opposite to the distal end in a second direction that the tubular member extends, the tubular member and the projection comprise a resin and are integrally formed, and the tubular member has a gate mark at a position closer to the proximal end than to a center of the tubular member in the second direction.

3. The microneedle of claim 2 , wherein the tubular member includes a flange that extends outward from an outer peripheral surface of the proximal end.

4. The microneedle of claim 1 , wherein the tubular member has the end surface at a distal end and has a proximal end opposite to the distal end in a second direction that the tubular member extends, and the tubular member further includes a flange that extends outward from an outer peripheral surface of the proximal end.

5. The microneedle of claim 1 , wherein the tubular member has a recess on an outer peripheral surface thereof.

6. The microneedle of claim 2 , wherein the tubular member has a recess on an outer peripheral surface thereof.

7. The microneedle of claim 3 , wherein the tubular member has a recess on an outer peripheral surface thereof.

8. The microneedle of claim 4 , wherein the tubular member has a recess on an outer peripheral surface thereof.

9. The microneedle of claim 1 , wherein the tubular member has a shape tapered toward the end surface.

10. The microneedle of claim 2 , wherein the tubular member has a shape tapered toward the end surface.

11. The microneedle of claim 3 , wherein the tubular member has a shape tapered toward the end surface.

12. The microneedle of claim 4 , wherein the tubular member has a shape tapered toward the end surface.

13. The microneedle of claim 5 , wherein the tubular member has a shape tapered toward the end surface.

14. The microneedle of claim 1 , wherein the projection has a pyramid or cone shape with a projection proximal end connected to the end surface of the tubular member, and the projection has the through hole extended from the projection proximal end to a side surface of the projection.

15. The microneedle of claim 2 , wherein the projection has a pyramid or cone shape with a projection proximal end connected to the end surface of the tubular member, and the projection has the through hole extended from the projection proximal end to a side surface of the projection.

16. The microneedle of claim 3 , wherein the projection has a pyramid or cone shape with a projection proximal end connected to the end surface of the tubular member, and the projection has the through hole extended from the projection proximal end to a side surface of the projection.

17. The microneedle of claim 4 , wherein the projection has a pyramid or cone shape with a projection proximal end connected to the end surface of the tubular member, and the projection has the through hole extended from the projection proximal end to a side surface of the projection.

18. The microneedle of claim 1 , wherein the projection has a prism or cylinder shape with a projection proximal end connected to the end surface of the tubular member, the projection has a tip portion having an inclined surface, and the projection has the through hole extended from the projection proximal end to the inclined surface.

19. The microneedle of claim 2 , wherein the projection has a prism or cylinder shape with a projection proximal end connected to the end surface of the tubular member, the projection has a tip portion having an inclined surface, and the projection has the through hole extended from the projection proximal end to the inclined surface.

20. The microneedle of claim 3 , wherein the projection has a prism or cylinder shape with a projection proximal end connected to the end surface of the tubular member, the projection has a tip portion having an inclined surface, and the projection has the through hole extended from the projection proximal end to the inclined surface.

Assignees

• Toppan Printing Co Ltd

Inventors

• Kodama Yoshihiro

Classifications

• B29C45/36

  having means for locating or centering cores · CPC title

• A61M37/0015 Primary

  by using microneedles · CPC title

• B29C45/261

  having tubular mould cavities · CPC title

• B29K2101/12

  Thermoplastic materials · CPC title

• A61M2037/003

  having a lumen · CPC title