Compositions and methods for improving viral vector efficiency
US-2018318447-A1 · Nov 8, 2018 · US
US10596264B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10596264-B2 |
| Application number | US-201214130285-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 28, 2012 |
| Priority date | Jun 30, 2011 |
| Publication date | Mar 24, 2020 |
| Grant date | Mar 24, 2020 |
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The invention relates to LAH4 peptides and functional derivatives thereof and their use for improving transduction efficiency of viruses into target cells.
Opening claim text (preview).
The invention claimed is: 1. A method for promoting the infection of an eukaryotic cell by a virus or a viral particle, comprising contacting a cell or a subject in need thereof with the virus or viral particle and with a peptide having the sequence of SEQ ID NO: 14. 2. An isolated peptide selected in the group consisting of SEQ ID NOs: 8-27. 3. A method for infecting eukaryotic cells with a virus or a viral particle or for increasing the eff…
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