Methods and systems for controlling body parts and devices using ipsilateral motor cortex and motor related cortex

Patent metadata

Field	Value
Publication number	US-10596014-B2
Application number	US-201715644201-A
Country	US
Kind code	B2
Filing date	Jul 7, 2017
Priority date	Jun 5, 2007
Publication date	Mar 24, 2020
Grant date	Mar 24, 2020

Abstract

A system for controlling a body part includes a number of sensing devices that sense signals from a hemisphere of a brain. A signal translating unit translates the signals into a command signal for controlling the body part, which is on a same side of the body as the hemisphere of the brain. A prosthetic device receives the command signal from the signal translating unit and manipulates the body part in response to the command signal.

First claim

What is claimed is:

1. A system for assisting with movement of a body part affected by a stroke event, comprising:
a brain signal acquisition system comprising a plurality of sensing devices that sense electrical brain signals from a brain of a subject having the body part affected by the stroke event, the plurality of sensing devices including sensing devices configured to sense electrical signals from a first hemisphere of the brain;
a signal translating unit that translates the sensed electrical brain signals from the first hemisphere of the brain into a command signal for controlling the affected body part, wherein the affected body part is on a same side of a body as the first hemisphere of the brain, wherein the signal translating unit further identifies, from sensed electrical brain signals acquired from the first hemisphere of the brain during a closed-loop brain computer interface control mode of operation, a subset of the sensed electrical brain signals having at least one cortical feature associated with ipsilateral movement that is distinct from a cortical feature associated with contralateral movement; and
a device that receives the command signal from the signal translating unit and assists with moving the body part in response to the command signal.

2. The system of claim 1 , wherein the plurality of sensing devices sense electrical brain signals are selected from the group consisting of devices that sense electrocortigraphic (ECoG) signals, electroencephalography (EEG) signals, local field potentials, single neuron signals, (MEG) magnetoencephalography signals, mu rhythm signals, beta rhythm signals, low gamma rhythm signals, and high gamma rhythm signals.

3. The system of claim 2 , wherein ECoG, EEG, local field potentials, and MEG signals include at least one of mu rhythm signals, beta rhythm signals, low gamma rhythm signals, and high gamma rhythm signals.

4. The system of claim 1 , wherein the plurality of sensing devices sense electrical brain signals from one of a primary motor cortex, a premotor cortex, a frontal lobe, a parietal lobe, a temporal lobe, and an occipital lobe of the brain.

5. The system of claim 1 , wherein the device that receives the command signal from the signal translating unit and assists with moving the body part is command signal is communicated to one of a robotic device, a transportation device, and a prosthetic control device.

6. The system of claim 1 , wherein the device that receives the command signal from the signal translating unit and assists with moving the body part is an external robotic assist device.

7. The system of claim 1 , wherein the device that receives the command signal from the signal translating unit and assists with moving the body part utilizes at least one of external nerve and muscle stimulators.

8. The system of claim 1 , wherein the device that receives the command signal from the signal translating unit and assists with moving the body part utilizes at least one of internally implanted nerve and muscle stimulators.

9. The system of claim 1 , wherein the body part comprises an arm of the subject on the same side of the subject as the first hemisphere of the brain, wherein the first hemisphere of the brain is largely unaffected by the stroke event, and wherein the device that assists in the movement of the body part assists in the movement of the arm.

10. The system of claim 9 , wherein the device that assists in the movement of the arm is a robotic exoskeleton.

11. The system of claim 1 , wherein the body part comprises a hand of the subject on the same side of the subject as the first hemisphere of the brain, wherein the first hemisphere of the brain is largely unaffected by the stroke event, and wherein the device that assists in the movement of the body part assists in the movement of the hand.

12. The system of claim 11 , wherein the device that assists in the movement of the hand is a robotic exoskeleton.

13. The system of claim 1 , wherein the signal translating unit converts the sensed electrical signals into a frequency domain and further determines spectral power changes for the sensed electrical signals in the frequency domain.

14. The system of claim 1 , wherein the at least one cortical feature associated with ipsilateral movement is initially identified during an open-loop screening process during which the subject performs actual or imagined movements of both (i) ipsilateral movements comprising movements of the affected body part on the same side of the subject as the first hemisphere of the brain, and (ii) contralateral movements comprising movements of an unaffected body part on the opposite side of the subject from the first hemisphere of the brain.

15. The system of claim 1 , wherein the at least one cortical feature associated with ipsilateral movement comprises spectral power changes being predominantly represented in a range of frequencies below 75 Hz.

16. The system of claim 15 , wherein the cortical feature associated with contralateral movement comprises spectral power changes being predominantly represented in a range of frequencies at or above 75 Hz.

17. The system of claim 1 , wherein the at least one cortical feature associated with ipsilateral movement comprises spectral power changes represented at an anterior/lateral location of the first hemisphere of the brain.

Assignees

• Univ Washington

Inventors

• Leuthardt Eric Claude
• Kreines Kimberly
• Anderson Nick

Classifications

• A61B5/0036

  including treatment, e.g., using an implantable medical device, ablating, ventilating · CPC title

• A61B5/4076

  Diagnosing or monitoring particular conditions of the nervous system · CPC title

• A61N1/36025

  for treating a mental or cerebral condition · CPC title

• A61F2002/6872

  attached and mechanically operated by remaining muscle · CPC title

• A61F2/72 Primary

  Bioelectric control, e.g. myoelectric · CPC title