Compounds having antiparasitic or anti-infectious activity
US-9206131-B2 · Dec 8, 2015 · US
US10584098B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10584098-B2 |
| Application number | US-201816110956-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 23, 2018 |
| Priority date | Jul 20, 2015 |
| Publication date | Mar 10, 2020 |
| Grant date | Mar 10, 2020 |
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Disclosed are derivative compounds of ELQ-300 that include an ester at position 4. These compounds have enhanced properties relative to ELQ-300. Also disclosed are pharmaceutical compositions comprising the compounds and methods of treating and preventing malaria infections involving administering the pharmaceutical compositions to the subject.
Opening claim text (preview).
The invention claimed is: 1. A compound selected from the group of: or a pharmaceutically acceptable salt thereof. 2. The compound of claim 1 selected from the group of: or a pharmaceutically acceptable salt thereof. 3. The compound of claim 1 which is: or a pharmaceutically acceptable salt thereof.
Antiparasitic agents · CPC title
attached in position 2 or 4 · CPC title
linked by a chain containing hetero atoms as chain links · CPC title
linked by a chain containing hetero atoms as chain links · CPC title
Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change · CPC title
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