Method for the treatment of skin disorders using dipeptide diaminobutyroyl benzylamide diacetate

US10561702B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10561702-B2
Application numberUS-201616060096-A
CountryUS
Kind codeB2
Filing dateDec 9, 2016
Priority dateDec 16, 2015
Publication dateFeb 18, 2020
Grant dateFeb 18, 2020

How to read this patent

A practical reading order for non-experts. Skip the full description unless you need deep technical detail.

  1. Title

    What the patent document calls the invention.

  2. Abstract

    A short plain-language summary of the technical disclosure.

  3. Assignees and inventors

    Who owns or filed the patent and who is credited as inventor.

  4. Key dates

    Filing, priority, publication, and grant dates set the timeline.

  5. First independent claim

    The legal scope of protection — read this for what is actually claimed.

  6. CPC / IPC classifications

    Technology tags used to group this patent with similar filings.

  7. Citations and related patents

    Prior art links and similar publications in this corpus.

Abstract

Official abstract text for this publication.

The present invention relates to a novel use of proline containing dipeptides for the prevention and/or treatment of skin conditions associated with altered, damaged or malfunctioning sebaceous glands.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for the treatment of sebaceous gland disorders selected from the group consisting of sebaceous hyperplasia, hyperseborrhea, acne, seborrheic dermatitis, atopic dermatitis and rosacea, wherein the method comprises topically administering to skin area of a person in need of such treatment an effective amount of a pharmaceutical composition comprising a dipeptidyl peptidase IV (DPP4) inhibitory effective amount of dipeptide diaminobutyroyl benzylamide diacetate. 2. The method according to claim 1 , wherein the amount of the dipeptide diaminobutyroyl benzylamide diacetate in the composition is in a range of 0.5 ppm to 5,000 ppm, based on the total weight of the composition. 3. The method according to claim 1 , which comprises topically applying the composition to the skin area in an amount of 0.1 to 3 mg/cm 2 skin. 4. The method according to claim 1 , wherein the composition is an O/W emulsion comprising an oily phase dispersed in an aqueous phase in the presence of an O/W emulsifier. 5. The method according to claim 4 , wherein the O/W emulsifier is potassium cetyl phosphate. 6. A method for the treatment of oily, shiny, blemished and/or blotchy skin and/or to reduce skin pore size, wherein the method comprises topically administering to skin area of a person in need of such treatment an effective amount of a cosmetic composition comprising a dipeptidyl peptidase IV (DPP4) inhibitory effective amount of dipeptide diaminobutyroyl benzylamide diacetate. 7. The method according to claim 6 , wherein the cosmetic composition is a skin care preparation. 8. The method according to claim 6 , wherein the amount of the dipeptide diaminobutyroyl benzylamide diacetate in the composition is in a range of 0.5 ppm to 5,000 ppm, based on the total weight of the composition. 9. The method according to claim 6 , which comprises topically applying the composition to the skin area in an amount of 0.1 to 3 mg/cm 2 skin. 10. The method according to claim 6 , wherein the composition is an O/W emulsion comprising an oily phase dispersed in an aqueous phase in the presence of an O/W emulsifier. 11. The method according to claim 10 , wherein the O/W emulsifier is potassium cetyl phosphate.

Assignees

Inventors

Classifications

  • Proteins; Peptides; Derivatives or degradation products thereof · CPC title

  • Preparations for oily skin · CPC title

  • A61K38/05Primary

    Dipeptides · CPC title

  • Preparations for care of the skin · CPC title

  • Anti-acne agents · CPC title

Patent family

Related publications grouped by family.

External sources

Frequently asked questions

Answers are generated from the same data shown on this page.

What does patent US10561702B2 cover?
The present invention relates to a novel use of proline containing dipeptides for the prevention and/or treatment of skin conditions associated with altered, damaged or malfunctioning sebaceous glands.
Who is the assignee on this patent?
Dsm Ip Assets Bv
What technology area does this patent fall under?
Primary CPC classification A61K38/05. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Feb 18 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 2 related publications on this page (citations in our corpus or others sharing the same primary CPC).