Oral care compositions and methods of use

Patent metadata

Field	Value
Publication number	US-10555883-B2
Application number	US-201615548857-A
Country	US
Kind code	B2
Filing date	Jun 24, 2016
Priority date	Jul 1, 2015
Publication date	Feb 11, 2020
Grant date	Feb 11, 2020

Abstract

This invention relates to oral care compositions comprising a basic amino acid in free or salt from (e.g., free form arginine); zinc oxide and zinc citrate; and a fluoride source comprising stannous fluoride.

First claim

What is claimed is:

1. An oral care composition comprising:
a. a basic amino acid in free or salt form, wherein the amino acid is L-arginine in an amount of about 1.5 wt. %;
b. zinc oxide and zinc citrate, wherein the zinc citrate is in an amount of about 0.5 wt. % and zinc oxide may be present in an amount of about 1.0 wt. % based on the total weight of the composition;
c. a fluoride source comprising stannous fluoride, wherein the stannous fluoride is present in an amount from 0.1 wt. % to 2 wt. % based on the total weight of the composition, and wherein the stannous fluoride provides about 750-7000 ppm fluoride; and
d. about 5% small particle silica, based on the total weight of the composition.

2. The oral care composition of claim 1 wherein the amino acid is arginine in free form.

3. The oral care composition of claim 1 wherein the amino acid is arginine partially or wholly in salt form.

4. The oral care composition of claim 1 , wherein the fluoride source further comprises at least one member selected from the group of: sodium fluoride, potassium fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride (e.g., N′-octadecyltrimethylendiamine-N,N,N′-tris(2-ethanol)-dihydrofluoride), ammonium fluoride, titanium fluoride, hexafluorosulfate, and combinations thereof.

5. The composition of claim 1 , wherein stannous fluoride provides soluble fluoride in an amount of about 1000-5500 ppm.

6. The composition of claim 1 , wherein stannous fluoride provides soluble fluoride in an amount of about 5000 ppm.

7. The oral care composition of claim 1 further comprising:
d. about 39.2% glycerin based on the total weight of the composition.

8. The oral care composition of claim 1 , wherein the oral composition may be any of the following oral compositions selected from the group consisting of: a toothpaste or a dentifrice, a mouthwash or a mouth rinse, a topical oral gel, and a denture cleanser.

Assignees

• Colgate Palmolive Co

Inventors

• Thomson Paul
• Dogu Nihal
• Prencipe Michael
• Russo Amy
• Stettler Hans
• Morgan Andre Michelle

Classifications

• A61P31/02

  Local antiseptics · CPC title

• A61P31/04

  Antibacterial agents · CPC title

• A61P1/02

  Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis · CPC title

• A61Q11/00

  Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title

• A61K8/44 Primary

  Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof · CPC title