Accommodating intraocular lens

Patent metadata

Field	Value
Publication number	US-10548718-B2
Application number	US-201514860162-A
Country	US
Kind code	B2
Filing date	Sep 21, 2015
Priority date	Mar 21, 2013
Publication date	Feb 4, 2020
Grant date	Feb 4, 2020

Abstract

An intraocular lens (IOL) for implantation within a capsular bag of a patient's eye comprises an optical structure and a haptic structure. The optical structure comprises a planar member, a plano convex member, and a fluid optical element defined between the planar member and the plano convex member. The fluid optical element has an optical power. The haptic structure couples the planar member and the plano convex member together at a peripheral portion of the optical structure. The haptic structure comprises a fluid reservoir in fluid communication with the fluid optical element and a peripheral structure for interfacing to the lens capsule. Shape changes of the lens capsule cause one or more of volume or shape changes to the fluid optical element in correspondence to deformations in the planar member to modify the optical power of the fluid optical element.

First claim

What is claimed is:

1. An accommodating intraocular lens, comprising:
a first component having a first optical structure and a first haptic reservoir portion, and the first optical structure being fixed at only its periphery;
a second component having a second optical structure and a second haptic reservoir portion, the second optical structure being fixed at only its periphery, and the second component being attached to the first component such that (a) the first optical structure is aligned with the second optical structure to form a fluid chamber between the first and the second optical structures that defines an optical element and (b) the first haptic reservoir portion is aligned with the second haptic reservoir portion to define a fluid reservoir having a deformable outer wall configured to engage a native capsule of an eye; and
an inner wall comprising a portion of at least one of the first component and the second component and extending between and separating the fluid chamber and the fluid reservoir, the inner wall comprising one or more openings;
wherein the fluid reservoir is fluidically coupled to the fluid chamber such that deformation of the outer wall causes fluid to flow through the one or more openings between the fluid reservoir and the fluid chamber; and
wherein a center region of the first optical structure is free to move under forces of a native eye capsule with respect to the second optical structure along a central anterior-posterior axis of the accommodating intraocular lens.

2. The accommodating intraocular lens as in claim 1 , wherein:
the first component comprises a polymer material;
the second component comprises the polymer material of the first component; and
the first and the second components are attached to each other with an adhesive at a seam between the first haptic reservoir portion and the second haptic reservoir portion, and the adhesive comprises a pre-polymer of the polymer material of the first and the second lens components.

3. The accommodating intraocular lens as in claim 2 , wherein the intraocular lens comprises a stiff configuration prior to implantation and a soft configuration when implanted and wherein the intraocular lens comprises the soft configuration when hydrated and each of the first component, the second component and a cured adhesive expand a substantially similar amount from the stiff configuration to the soft configuration thereby inhibiting stress at interfaces between the cured adhesive and the first and the second components.

4. The accommodating intraocular lens as in claim 2 , wherein the pre-polymer is selected from ethylene glycol dimethacrylate (EGDMA), diethylene glycol dimethacrylate (DEGDMA), triethylene glycol trimethacrylate (TEGDMA), hydroxyethyl methacrylate (HEMA), and methyl methacrylate (MMA).

5. The accommodating intraocular lens as in claim 2 , wherein the adhesive comprises a monomer, an oligomer, a partially cured monomer, particles, or nanoparticles of the polymer material.

6. The accommodating intraocular lens as in claim 1 , further comprising a fluid within the chamber having an index of refraction greater than approximately 1.336 and wherein one or more of the first component or the second component is configured to deform to increase an optical power of the accommodating intraocular lens.

7. The accommodating intraocular lens as in claim 1 , wherein the outer wall of the fluid reservoir is configured to engage a wall of the native capsule of the eye and increase curvature of one or more of the first optical structure or the second optical structure in response to the wall of the capsular bag contracting and thereby increase optical power of the accommodating intraocular lens.

8. The accommodating intraocular lens as in claim 1 , further comprising a fluid in the fluid reservoir and the chamber, the fluid comprising one or more of a solution, an oil, a silicone, a silicone oil, a solution of high molecular weight molecules or high molecular weight dextran.

9. The accommodating intraocular lens as in claim 1 , the seam extends continuously circumferentially around the fluid reservoir.

10. The accommodating intraocular lens as in claim 1 , wherein the first optical structure comprises a first disc shaped optical structure comprising one or more of a lens, a meniscus, a meniscus lens, or a flat plate, and wherein the second optical structure comprises a second disc shaped optical structure comprising one or more of a lens, a meniscus, a meniscus lens, or a flat plate.

11. The accommodating intraocular lens as in claim 1 , wherein the first component and the second component are of the same polymer material.

12. The accommodating intraocular lens as in claim 1 , wherein a change in optical power of the accommodating intraocular lens comprises a response to a transfer of fluid into or out of the chamber from the fluid reservoir defined between the first and the second lens components.

13. The accommodating intraocular lens as in claim 1 , wherein water present in the lens capsule of the native capsule of the eye transfers into or out of the chamber through a polymeric material of the first and the second lens components to achieve an osmotic equilibrium with fluid present in the lens capsule when the intraocular lens is placed therein.

14. The accommodating intraocular lens as in claim 1 , wherein the intraocular lens is configured to be folded into a reduced cross-section delivery configuration; wherein the reduced cross-section delivery configuration of the intraocular lens is attained by folding or rolling the intraocular lens around a delivery axis normal to the central anterior-posterior axis of the intraocular lens; and wherein the reduced cross-section delivery configuration of the intraocular lens is attained by advancing the intraocular lens through a delivery tube or aperture.

15. The accommodating intraocular lens as in claim 1 , wherein the first optical structure comprises a first lens, the second optical structure comprises a second lens, and a center region of the first lens is free to move with respect to the second lens along the central anterior-posterior axis of the accommodating intraocular lens.

16. The accommodating intraocular structure of claim 15 , wherein the first and the second lenses comprise first and second membranes, respectively.

17. The accommodating intraocular lens as in claim 1 , wherein the first and the second optical structures are configured such that maximum displacement between the first and the second optical structures occurs along the central anterior-posterior optical axis of the accommodating intraocular lens.

18. The accommodating intraocular lens as in claim 1 , further comprising spacers spaced apart from each other circumferentially around the first and the second optical structures.

19. The accommodating intraocular lens as in claim 1 , wherein in the optical structures are adhered to each other at only their peripheries.

20. An accommodating intraocular lens, comprising:
a first component having a first optical structure and a first haptic reservoir portion; and
a second component having a second optical structure and a second haptic reservoir portion, the second component being attached to the first component such that (a) the first optical structure is aligned with the second optical structure to form a fluid chamber between the first and the second optical structures that defines an optical element, (b) the first haptic reservoir portion is aligned with the second haptic reservoir po

Assignees

• Shifamed Holdings Llc

Inventors

• Salahieh Amr
• Argento Claudio R
• Saul Tom
• Vaughan Bob
• Willis Eric

Classifications

• A61F2250/0018

  differing in elasticity, stiffness or compressibility · CPC title

• A61F2/1601 Primary

  Lens body having features to facilitate aqueous fluid flow across the intraocular lens, e.g. for pressure equalization or nutrient delivery · CPC title

• A61F2002/1681

  having supporting structure for lens, e.g. haptics · CPC title

• A61F2/1648

  Multipart lenses · CPC title

• A61F2/1613

  having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus · CPC title