Medical fluid cassette leak detection methods and devices

Patent metadata

Field	Value
Publication number	US-10539481-B2
Application number	US-201715399043-A
Country	US
Kind code	B2
Filing date	Jan 5, 2017
Priority date	Mar 14, 2013
Publication date	Jan 21, 2020
Grant date	Jan 21, 2020

Abstract

A method is provided for detecting leaks in a disposable medical fluid cassette that includes a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway. The method includes applying a first force to the flexible membrane, measuring a first physical property of a system that includes the medical fluid cassette a medical fluid pumping machine, removing the first force from the flexible membrane, applying a second force to the flexible membrane, measuring a second physical property of the system, and determining whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.

First claim

What is claimed is:

1. A medical fluid pumping machine configured to receive a disposable medical fluid cassette, the medical fluid cassette comprising a base and a flexible membrane attached to the base in such a way that the base and the flexible membrane cooperate to at least partially form a fluid passageway, the medical fluid pumping machine comprising:
a compartment that receives the medical fluid cassette,
a pressure applicator configured to apply a force to the medical fluid cassette when the medical fluid cassette is disposed within the compartment;
a processer that is configured to
control the pressure applicator in such a way that a first force is applied to the flexible membrane when the medical fluid cassette is disposed within the compartment;
measure a first physical property of a system that includes the medical fluid pumping machine with the medical fluid cassette disposed within the compartment while the first force is applied to the flexible membrane;
control the pressure applicator in such a way that the first force is removed from the flexible membrane when the medical fluid cassette is disposed within the compartment;
control the pressure applicator in such a way that a second force is applied to the flexible membrane when the medical fluid cassette is disposed within the compartment;
measure a second physical property of the system that includes the medical fluid pumping machine with the medical fluid cassette disposed within the compartment while the second force is applied to the flexible membrane; and
determine whether the medical fluid cassette leaks based on a comparison of the first physical property and the second physical property.

2. The medical fluid pumping machine of claim 1 , comprising
a door that is configured to selectively close the compartment and retain the medical fluid cassette within the compartment, and
an inflatable bladder disposed on an inside surface of the door and configured such that
when inflated while the medical fluid cassette is within the compartment, the inflatable bladder is configured to compress the medical fluid cassette, and
when deflated while the medical fluid cassette is within the compartment, the inflatable bladder is configured to contract against the inside surface of the door and generate a space between the inflatable bladder and the medical fluid cassette, wherein

the processer is configured to deflate the door bladder between controlling the pressure applicator in such a way that the first force is removed from the flexible membrane and controlling the pressure applicator in such a way that the second force is applied to the flexible membrane.

3. The medical fluid pumping machine of claim 1 wherein the medical fluid cassette includes fluid inlet ports and fluid outlet ports that provide communication between the fluid passageway and an exterior of the medical fluid cassette, and
the processer is configured to close the fluid inlet ports and fluid outlet ports after controlling the pressure applicator in such a way that the first force is applied to the flexible membrane and before measuring the first pressure within the medical fluid cassette.

4. The medical fluid pumping machine of claim 1 wherein the medical fluid cassette includes fluid inlet ports and fluid outlet ports that provide communication between the fluid passageway and an exterior of the medical fluid cassette, and
controlling the pressure applicator in such a way that the first force is applied to the flexible membrane is performed with the fluid inlet ports and fluid outlet ports closed.

5. The medical fluid pumping machine of claim 1 , comprising a vacuum source controllable by the processor and disposed within the compartment in a manner such that, when activated while the medical fluid cassette is within the compartment, the vacuum source is configured to apply a force to the flexible membrane, and
the processor is configured to change a spacing between the flexible membrane and the base by activating the vacuum source.

6. The medical fluid pumping machine of claim 5 , wherein the processor is configured to change the spacing after controlling the pressure applicator in such a way that the first force is removed from the flexible membrane and before controlling the pressure applicator in such a way that the second force is applied to the flexible membrane.

7. The medical fluid pumping machine of claim 5 , wherein the vacuum source is configured to apply a force to an outer surface of the flexible membrane.

8. The medical fluid pumping machine of claim 1 wherein controlling the pressure applicator in such a way that the first force is applied to the flexible membrane comprises controlling the pressure applicator in such a way that the flexible membrane is compressed against the base.

9. The medical fluid pumping machine of claim 8 wherein the pressure applicator comprises a piston configured to be advanced into and retracted from the compartment.

10. The medical fluid pumping machine of claim 8 wherein the medical fluid cassette includes fluid inlet ports and fluid outlet ports that provide communication between the fluid passageway and an exterior of the medical fluid cassette, and
controlling the pressure applicator in such a way that the first force is applied to the flexible membrane is performed with the fluid inlet ports and fluid outlet ports open.

Assignees

• Fresenius Medical Care Holdings Inc

Inventors

• Plahey Kulwinder S
• Zhu Jie
• Ly Tri
• Ohline Robert Matthew
• Crawford William Scott

Classifications

• A61M2205/121

  interface between cassette and base · CPC title

• A61M2205/15

  Detection of leaks · CPC title

• A61M2205/123

  with incorporated reservoirs · CPC title

• A61M2205/12

  with interchangeable cassettes forming partially or totally the fluid circuit · CPC title

• G01M3/36

  by detecting change in dimensions of the structure being tested · CPC title