Selection and use of lactic acid bacteria preventing bone loss in mammals

US10537598B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-10537598-B2
Application numberUS-201916254994-A
CountryUS
Kind codeB2
Filing dateJan 23, 2019
Priority dateJun 4, 2012
Publication dateJan 21, 2020
Grant dateJan 21, 2020

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  1. Title

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  2. Abstract

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  3. Assignees and inventors

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The present invention comprises a method for selecting lactic acid bacterial strains effective for preventing bone loss in humans and strains that have been selected according to the presented method. The selection method is based on the strains capability of reestablishing an altered microbial community to normal and/or harboring at least one of four specific SNPs.

First claim

Opening claim text (preview).

The invention claimed is: 1. A method for preventing or treating bone loss, comprising administering to an individual in need thereof a lactic acid bacterial strain comprising a nucleic acid sequence having at least 99% identity to the nucleic acid sequence of the genome of L. reuteri JCM 1112 (SEQ ID NO:1), and wherein the lactic acid bacterial strain harbors a nucleotide relative to the genome of Lactobacillus reuteri JCM 1112 (SEQ ID NO: 1) in all of the following four positions: C in base pair 271 391, G in base pair 453 538, G in base pair 529 228, and C in base pair 599 338. 2. The method of claim 1 , wherein the bone loss is osteopenic and/or osteoporotic bone loss.

Assignees

Inventors

Classifications

  • for osteoporosis · CPC title

  • for bone diseases, e.g. rachitism, Paget's disease · CPC title

  • Drugs for skeletal disorders · CPC title

  • Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems · CPC title

  • Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

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What does patent US10537598B2 cover?
The present invention comprises a method for selecting lactic acid bacterial strains effective for preventing bone loss in humans and strains that have been selected according to the presented method. The selection method is based on the strains capability of reestablishing an altered microbial community to normal and/or harboring at least one of four specific SNPs.
Who is the assignee on this patent?
Biogaia Ab, Univ Michigan State
What technology area does this patent fall under?
Primary CPC classification A61K35/747. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Jan 21 2020 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).