Drug administration device, and manufacturing method for drug administration device

Patent metadata

Field	Value
Publication number	US-10532201-B2
Application number	US-201715701216-A
Country	US
Kind code	B2
Filing date	Sep 11, 2017
Priority date	Mar 18, 2015
Publication date	Jan 14, 2020
Grant date	Jan 14, 2020

Abstract

A drug administration device includes a substrate having a first surface, a projection extending from the first surface, and a solid drug. One direction that intersects with the first surface is a first direction, and one direction that extends along the first surface is a second direction. A groove serving as a receiving section is formed in the projection. The groove defines a cavity recessed in the first direction toward the substrate and extends in the second direction to open to a section of the peripheral surface of the projection. The drug is received in the groove.

First claim

The invention claimed is:

1. A drug administration device comprising:
a substrate having a first surface;
a projection extending from the first surface and including a peripheral surface; and
a solid drug, wherein
the projection includes a receiving section,
the receiving section defines a cavity recessed in a first direction that intersects with the first surface toward the substrate and extends in a second direction that extends along the first surface to open to a section of the peripheral surface of the projection,
the projection includes a pointed distal end having an apex,
the projection includes a quadrilateral upper surface inclined relative to the first surface, the apex of the projection being positioned on the quadrilateral upper surface,
as viewed facing the first surface, the apex is located on an edge of the projection,
the receiving section extends through the projection in the second direction and from a first side of the quadrilateral upper surface to a second side of the quadrilateral upper surface that is opposite to the first side, the first side extending from the apex of the projection, and
the drug is received in the receiving section.

2. The drug administration device according to claim 1 , wherein the drug is a freeze-dried drug.

3. The drug administration device according to claim 1 , wherein
the receiving section is a groove having a bottom, and
the bottom of the groove is located at a position separated from the substrate in the first direction.

4. The drug administration device according to claim 1 , wherein
the projection is one of a plurality of projections, and
all of the projections have the same second direction.

5. A method for manufacturing a drug administration device according to claim 1 , comprising:
a first step of fabricating a main body, wherein the main body includes the substrate and the projection;
a second step of loading a liquid drug into the receiving section; and
a third step of drying the drug loaded in the receiving section.

6. The method for manufacturing a drug administration device according to claim 5 , wherein the third step includes freeze-drying the drug.

Assignees

• Toppan Printing Co Ltd
• Japan As Represented By Director General Of Natl Inst Of Infectious Diseases
• Japan As Represented By Director General Of Nat Institute Of Infectious Diseases

Inventors

• Kato Hiroyuki
• Sumida Tomoya
• Kodama Yoshihiro
• Naito Seishiro

Classifications

• A61M2037/003

  having a lumen · CPC title

• A61M37/00

  Other apparatus for introducing media into the body (for reproduction or fertilisation A61B17/425; apparatus for iontophoresis or cataphoresis A61N1/30); Percutany, i.e. introducing medicines into the body by diffusion through the skin (salt baths A61H33/04) · CPC title

• A61M2037/0053

  Methods for producing microneedles · CPC title

• A61M37/0015 Primary

  by using microneedles · CPC title