Water soluble farnesol analogs and their use

Patent metadata

Field	Value
Publication number	US-10532124-B2
Application number	US-201214655359-A
Country	US
Kind code	B2
Filing date	Dec 27, 2012
Priority date	Dec 27, 2012
Publication date	Jan 14, 2020
Grant date	Jan 14, 2020

Abstract

Farnesol analogs, along with their related products (e.g., treatment compositions, wipes, absorbent articles, etc.) and their methods of formation, are provided. The farnesol analog includes a hydrophilic end group (e.g., a hydroxyl end group or a carboxylic acid end group) attached to farnesol via a covalent linkage (e.g., an ester group or an ether group).

First claim

What is claimed is:

1. A farnesol analog comprising a hydrophilic end group attached to farnesol via a covalent linkage, wherein the hydrophilic end group defines a hydroxyl end group, and wherein the covalent linkage comprises an ester group or an ether group, wherein the farnesol analog comprises one of the structures:

where n is an integer from 1 to 8; m is an integer from 1 to 8; and p is an integer from 1 to 100.

2. The farnesol analog as in claim 1 , wherein the covalent linkage comprises an ester group.

3. The farnesol analog as in claim 1 , wherein n is 2, 3, or 4.

4. The farnesol analog as in claim 3 , wherein the hydrophilic end group comprises an ester group.

5. The farnesol analog as in claim 1 , wherein n is 2, 3, or 4; and wherein m is 2, 3, or 4.

6. The farnesol analog as in claim 1 , wherein the covalent linkage comprises an ether group, and wherein the hydrophilic end group defines a hydroxyl end group.

7. The farnesol analog as in claim 1 , wherein the farnesol analog has a solubility in water that is 10 grams per 100 grams of water or greater.

8. A web comprising a plurality of fibers, wherein the web is coated with a treatment composition, the treatment composition comprising a farnesol analog according to claim 1 .

9. An absorbent article comprising:
a liquid impermeable outer cover;
a liquid permeable bodyside liner, wherein the bodyside liner comprises the web according to claim 8 ; and
an absorbent body disposed between the outer cover and bodyside liner.

10. A method of forming a farnesol analog that is soluble in water from a farnesol molecule having a hydroxyl group, the method comprising:
covalently attaching a hydrophilic end group to the farnesol molecule via reaction with its hydroxyl group to form a covalent linkage, wherein the hydrophilic end group defines a hydroxyl end group, and wherein the covalent linkage comprises an ester group or an ether group, wherein the farnesol analog comprises one of the structures:

where n is an integer from 1 to about 8; m is an integer from 1 to 8; and p is an integer from 1 to 100.

11. The method as in claim 10 , wherein the covalent linkage comprises an ester group formed via an esterification reaction between the hydroxyl group of the farnesol molecule and a carboxylic acid functional molecule.

12. The method as in claim 11 , further comprising:
reacting the carboxylic acid end group with a glycol via a second esterification reaction to form a farnesol analog having a hydroxyl group covalently attached via two ester linkages.

13. The method as in claim 12 , wherein the glycol is selected from the group consisting of ethylene glycol, propylene glycol, and butane-1,4-diol.

14. The method as in claim 10 , wherein the covalent linkage comprises an ether group formed by reacting farnesol with an alcohol via a dehydration reaction to form the ether group.

15. The method as in claim 14 , wherein the alcohol is a glycol selected from the group consisting of ethylene glycol, propylene glycol, and butane-1,4-diol.

16. The method as in claim 14 , wherein the hydrophilic end group comprises a sugar.

17. A wipe comprising the web according to claim 8 .

Assignees

• Kimberly Clark Co

Inventors

• Koenig David William
• Foegen Mary Kay
• Cunningham Corey Thomas
• He Aimin
• Huang Yang

Classifications

• C07C69/007

  Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom · CPC title

• C07C33/02

  Acyclic alcohols with carbon-to-carbon double bonds · CPC title

• A61L15/44 Primary

  Medicaments · CPC title

• A61L15/20 Primary

  containing organic materials · CPC title

• A61L15/62

  {Compostable,} hydrosoluble or hydrodegradable materials · CPC title