Molecular detection apparatus, molecular detection method, and organic probe

Patent metadata

Field	Value
Publication number	US-10527581-B2
Application number	US-201715699161-A
Country	US
Kind code	B2
Filing date	Sep 8, 2017
Priority date	Sep 10, 2015
Publication date	Jan 7, 2020
Grant date	Jan 7, 2020

Abstract

A molecular detection apparatus according to an embodiment includes a detector and a discriminator. The detector includes a plurality of detection cells, where the plurality of detection cells include at least an organic probe containing a cyano group or a nitro group as a neighboring group of a reactive group. The discriminator discriminates a substance to be detected by signal patterns of the plurality of detection cells.

First claim

What is claimed is:

1. A molecular detection apparatus, comprising:
a detector which includes a detection cell having an organic probe,
wherein the organic probe is made of a first organic compound including a head portion which has a monovalent aromatic hydrocarbon group containing a hydroxyl group as a reactive group and a cyano group or a nitro group, a base portion which has a monovalent polycyclic aromatic hydrocarbon group, and a connecting portion which has a bivalent group connecting the head portion and the base portion.

2. The apparatus according to claim 1 ,
wherein the first organic compound contains a cyanohydrin derivative.

3. The apparatus according to claim 1 ,
wherein the detection cell includes a sensor unit where the organic probe is provided, and
wherein the sensor unit includes a field effect transistor having a graphene layer and electrodes connected to the graphene layer.

4. The apparatus according to claim 1 ,
wherein the detector includes a first detection cell which has a first organic probe made of the first organic compound, and a second detection cell which has a second organic probe made of a second organic compound which is different from the first organic compound, and
wherein the second organic compound includes a head portion which has a monovalent aromatic hydrocarbon group containing a hydroxyl group as a reactive group and a trifluoromethyl group, a base portion which has a monovalent polycyclic aromatic hydrocarbon group, and a connecting portion which has a bivalent group connecting the head portion and the base portion.

5. The apparatus according to claim 4 ,
wherein the detector further includes a third detection cell which does not have the organic probe.

6. The apparatus according to claim 1 ,
wherein the detector includes a first detection cell which has a first organic probe made of the first organic compound having the cyano group, a second detection cell which has a second organic probe made of the first organic compound having the nitro group, and a third detection cell which has a third organic probe made of a second organic compound which is different from the first organic compound, and
wherein the second organic compound includes a head portion which has a monovalent aromatic hydrocarbon group containing a hydroxyl group as a reactive group and a trifluoromethyl group, a base portion which has a monovalent polycyclic aromatic hydrocarbon group, and a connecting portion which has a bivalent group connecting the head portion and the base portion.

7. The apparatus according to claim 6 ,
wherein the detector further includes a fourth detection cell which does not have the organic probe.

8. The apparatus according to claim 1 ,
wherein a substance to be detected is a compound containing phosphorus.

9. The apparatus according to claim 1 ,
wherein the detector includes a plurality of the detection cells, and
wherein at least one of the detection cells has the organic probe made of the first organic compound.

10. The apparatus according to claim 9 , further comprising:
a discriminator which discriminates a substance to be detected by a signal pattern of the plurality of detection cells.

11. The apparatus according to claim 9 ,
wherein one of the detection cells has a first organic probe made of the first organic compound, and
wherein another one of the detection cells has a second organic probe made of a second organic compound which is different from the first organic compound.

12. The apparatus according to claim 9 ,
wherein each of the detection cells has the organic probe made of the first organic compound.

13. The apparatus according to claim 1 ,
wherein the hydroxyl group and the cyano group or the nitro group are bonded to a same carbon in the monovalent aromatic hydrocarbon group.

Assignees

• Toshiba Kk

Inventors

• Yamada Ko
• Yoshimura Reiko
• Miyamoto Hirohisa
• Osada Norikazu
• Oki Mitsuhiro
• Nakamura Hiroko

Classifications

• G01N27/4148 Primary

  Integrated circuits therefor, e.g. fabricated by CMOS processing · CPC title

• G01N27/4141

  specially adapted for gases · CPC title

• G01N33/0036

  specially adapted to detect a particular component (physical analysis of gaseous biological material G01N33/497) · CPC title

• G01N27/4146

  involving nanosized elements, e.g. nanotubes, nanowires · CPC title

• B82Y30/00

  Nanotechnology for materials or surface science, e.g. nanocomposites · CPC title