System and method for scoring the left ventricular endocardium to increase left ventricular compliance

Patent metadata

Field	Value
Publication number	US-10512482-B2
Application number	US-201314433763-A
Country	US
Kind code	B2
Filing date	Oct 7, 2013
Priority date	Oct 5, 2012
Publication date	Dec 24, 2019
Grant date	Dec 24, 2019

Abstract

In some embodiments, a system for scoring human endocardium tissue may include a first conduit and an activation system. The first conduit may include a first opening, a second opening, and a cutting device. The first opening may be positioned at a proximal end of the first conduit. The second opening may extend from adjacent to a closed distal end portion of the first conduit. The cutting device, when activated, may cut through a portion of a depth of endocardium tissue positioned adjacent the second opening. The cutting device may selectively cut or score the endocardium to a specified depth and length in the endocardium of a left ventricle of a human heart.

First claim

What is claimed is:

1. A method of ameliorating diastolic dysfunction, comprising:
positioning a second conduit in a human body such that a distal end of the second conduit is positioned in a left ventricle of a human heart;
positioning a first conduit in the second conduit such that a distal end of the first conduit extends beyond the distal end of the second conduit into the left ventricle;
activating a cutting device to sever at least one trabeculae carneae while inhibiting damage to cardiac tissue directly attached to the severed trabeculae carneae; and
releasing pressure on the human heart.

2. The method of claim 1 , further comprising forming an opening in an apex of the left ventricle.

3. The method of claim 1 , further comprising severing at least one trabeculae carneae adjacent an apex of the left ventricle.

4. The method of claim 1 , wherein severing the at least one trabeculae releases at least some of the elastic forces on the left ventricle.

5. A method of ameliorating diastolic dysfunction, comprising:
positioning a second conduit in a human body such that a distal end of the second conduit is positioned in a left ventricle of a human heart;
positioning a first conduit in the second conduit such that a distal end of the first conduit extends beyond the distal end of the second conduit into the left ventricle;
activating a cutting device to sever at least one trabeculae carneae adjacent an apex of the left ventricle while inhibiting damage to cardiac tissue directly attached to the severed trabeculae carneae; and
releasing at least some of the elastic forces on the left ventricle.

6. The method of claim 5 , further comprising forming an opening in an apex of the left ventricle.

7. The method of claim 5 , further comprising releasing pressure on the human heart.

8. A system for ameliorating diastolic dysfunction, comprising:
a first conduit, comprising:
a first opening positioned at a proximal end of the first conduit extending through the proximal end in communication with a first lumen extending through the first conduit;
a second opening extending from adjacent to a distal end portion of the first conduit;
a shaping member positionable in the distal portion of the first conduit, wherein the shaping member substantially conforms to a portion of a perimeter or endocardium of a left ventricle upon activation when exposed to elevated temperatures associated with the human body;
a cutting device positioned in the distal portion of the first conduit, wherein the cutting device, when activated, extends out of the second opening of the first conduit and severs, during use, at least one trabeculae carneae; and

an activation system for activating the cutting device.

9. The system of claim 8 , wherein activating the cutting device comprises retracting at least a portion of a sheath from a first position covering at least a portion of the second opening to a second position exposing the portion of the second opening.

10. The system of claim 8 , wherein the cutting device comprises a blade.

11. The system of claim 8 , wherein the cutting device comprises a serrated blade.

12. The system of claim 8 , wherein the cutting device comprises a blade comprising an arcuate shape in an orientation such that a distal end of the blade penetrates.

13. The system of claim 8 , wherein the shaping member, when activated during use, changes from a first shape to a second shape, wherein the first shape is substantially straight and the second shape substantially conforms to a portion of a perimeter or endocardium of a left ventricle.

14. The system of claim 8 , wherein the shaping member, when activated during use, changes from a first shape to a second shape, wherein the first shape is substantially straight and the second shape substantially conforms to a portion of a perimeter or endocardium of a left ventricle.

Assignees

• Univ Texas

Inventors

• Feldman Marc D
• Escobedo Daniel
• Halaney David L
• Dwelle Jordan C
• Mcelroy Austin B
• Milner Thomas E

Classifications

• A61B2017/00243

  cardiac · CPC title

• A61B2017/00247

  Making holes in the wall of the heart, e.g. laser Myocardial revascularization · CPC title

• A61B17/00234

  for minimally invasive surgery (A61B17/0218, A61B17/0469, A61B17/12013, A61B17/1285, A61B17/29, A61B17/320016 take precedence) · CPC title

• A61B2017/320052

  Guides for cutting instruments · CPC title

• A61B17/320016 Primary

  Endoscopic cutting instruments, e.g. arthroscopes, resectoscopes (A61B10/0233, A61B17/29, A61B17/3207 take precedence) · CPC title