Handheld dyspnea treatment device with drug and gas delivery

Patent metadata

Field	Value
Publication number	US-10507294-B2
Application number	US-201314420151-A
Country	US
Kind code	B2
Filing date	Jul 30, 2013
Priority date	Aug 13, 2012
Publication date	Dec 17, 2019
Grant date	Dec 17, 2019

Abstract

A portable handheld pressure support system configured to provide rapid recovery from dyspnea of a subject is provided. The pressure support system is configured to be small and lightweight so that the subject carries the system and use the system as needed without requiring a device to be worn on the face. The system includes one or more of a pressure generator, a subject interface, a medicament inlet port, one or more sensors, one or more valves, one or more processors, a user interface, electronic storage, a portable power source, a housing, a handle, and/or other components.

First claim

What is claimed is:

1. A portable handheld pressure support system configured to provide recovery from dyspnea of a subject, without needing to be worn by the subject, the pressure support system comprising:
a pressure generator configured to generate a pressurized flow of breathable gas for delivery to an airway of the subject;
a subject interface configured to communicate the pressurized flow of breathable gas to the airway of the subject;
a medicament inlet port configured to couple to a supply that includes medicament;
one or more valves configured to selectively control a flow including medicament through the medicament inlet port;
one or more sensors configured to generate output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas and one or more flow parameters of the flow including medicament flowing through the medicament inlet port;
one or more processors configured to execute computer program modules, the computer program modules comprising:
a generator control module configured to control operation of the pressure generator to generate the pressurized flow of breathable gas based on the output signals from the one or more sensors, in accordance with a positive pressure support therapy regime,
a medicament module configured to obtain a flow including medicament for inhalation by the subject, and
a valve control module configured to control the one or more valves in order to release the obtained flow including medicament into the pressurized flow of breathable gas for inhalation by the subject based on the output signals, from the one or more sensors, conveying the information related to the one or more gas parameters of the pressurized flow of breathable gas and the one or more flow parameters of the flow including medicament flowing through the medicament inlet port;

a portable power source configured to power the pressure generator, the one or more sensors, the one or more valves, and the one or more processors;
a housing configured to contain the pressure generator, the subject interface, the one or more sensors, the medicament inlet port, the one or more valves, the one or more processors, and the power source; and
a handle attached to and/or formed by the housing configured to be grasped by a hand of the subject to hold the housing such that the subject interface is carried with the housing into position with respect to the airway of the subject as the pressurized flow of breathable gas is delivered to the airway of the subject.

2. The system of claim 1 , wherein the maximum volume of the housing is 135 cubic inches.

3. The system of claim 1 , wherein the computer program modules further comprise:
a respiratory phase transition module configured to determine the start of inhalation for a respiratory cycle of the subject, wherein the determination made by the respiratory phase transition module are based on the output signals, wherein the valve control module is further configured, responsive to a determination by the respiratory phase transition module that the subject has started an inhalation, to control the one or more valves in order to release the obtained flow including medicament into the pressurized flow of breathable gas for inhalation by the subject.

4. The system of claim 1 , wherein the computer program modules further comprises: a recovery quantification module configured to determine whether respiration by the subject indicates that the subject can effectively process the medicament, wherein the valve control module is further configured to initiate the release of the obtained flow including medicament into the pressurized flow of breathable gas based on a determination by the recovery quantification module.

5. The system of claim 1 , further comprising:
a blending gas inlet port configured to obtain a flow of blending gas for inhalation by the subject, wherein the one or more sensors are further configured to generate the output signals conveying information related to one or more gas parameters of the flow of blending gas flowing through blending gas inlet port,
wherein the one or more valves are further configured to selectively control the flow of blending gas through the blending gas inlet port, and
wherein the valve control module is further configured to control the one or more valves in order to release the obtained flow of blending gas into the pressurized flow of breathable gas for inhalation by the subject based on the output signals from the one or more sensors.

6. A method of controlling and operating a handheld pressure support system that includes a housing that includes a pressure generator, a subject interface, one or more sensors, a medicament inlet port, one or more valves, one or more processors, the housing forming and/or being attached to a handle, and a power source, the method comprising:
generating a pressurized flow of breathable gas by the pressure generator;
communicating the pressurized flow of breathable gas to an airway of a subject with the subject interface;
coupling, by the medicament inlet port, the housing to a supply that includes medicament;
generating output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas and one or more flow parameters of a flow including medicament flowing through the medicament inlet port by the one or more sensors;
selectively controlling, by the one or more valves, the flow including medicament through the medicament inlet port;
controlling generation of the pressurized flow of breathable gas based on the output signals from the one or more sensors, in accordance with a positive pressure support therapy regime;
obtaining the flow including medicament for inhalation by the subject;
controlling the one or more valves in order to release the obtained flow of medicament into the pressurized flow of breathable gas for inhalation by the subject based on the output signals, from the one or more sensors, conveying the information related to the one or more gas parameters of the pressurized flow of breathable gas and the one or more flow parameters of the flow including medicament flowing through the medicament inlet port;
portably powering, by the power source, the pressure generator, the one or more sensors, the one or more valves, and the one or more processors;
grasping by a hand of the subject, the handle to hold the housing such that the subject interface is carried with the housing into position with respect to the airway of the subject as the pressurized flow of breathable gas is delivered to the airway of the subject.

7. The method of claim 6 , wherein a maximum volume of the housing is 135 cubic inches.

8. The method of claim 6 , further comprising:
determining the start of inhalation and/or the start of exhalation for a respiratory cycle of the subject based on the output signals, and wherein controlling the one or more valves in order to release the obtained flow of medicament is responsive to a determination for the respiratory cycle of the subject.

9. The method of claim 6 , further comprising:
obtaining an effectiveness determination whether respiration by the subject indicates that the subject can effectively process the medicament, wherein controlling the one or more valves in order to release the obtained flow of medicament is based on the effectiveness determination.

10. The method of claim 6 , wherein the housing further includes a blending gas inlet port, the method further comprising:
coupling, by the blending gas inlet port, the housing to a supply of blending gas;
selectively controlling, by the one or more valves, a flow of blending gas through the blending gas i

Assignees

• Koninklijke Philips Nv

Inventors

• Mahadevan Anandi
• Diacopoulso Elias George

Classifications

• A61M11/00

  Sprayers or atomisers specially adapted for therapeutic purposes (in general B05B; {aerosol containers B65D83/14}) · CPC title

• A61M16/024

  including calculation means, e.g. using a processor · CPC title

• A61M2205/3334

  Measuring or controlling the flow rate · CPC title

• A61M2230/63

  Motion, e.g. physical activity · CPC title

• A61M16/1055

  bacterial · CPC title