Method of filling a container

Patent metadata

Field	Value
Publication number	US-10507273-B2
Application number	US-201515309625-A
Country	US
Kind code	B2
Filing date	May 7, 2015
Priority date	May 8, 2014
Publication date	Dec 17, 2019
Grant date	Dec 17, 2019

Abstract

A method of filling a container, preferably containing at least one concentrate, with the concentrate being formed such that it forms at least one liquid concentrate or a part of a liquid concentrate on its solution in or its mixing with a liquid, preferably water, the liquid concentrate or the part of the liquid concentrate being suitable for preparing at least one dialysis solution, includes filling the container via a balance chamber system of a dialyzer. The balance chamber system has chambers from which the liquid is conveyed into the container in the form of repeating cycles. The pressure of the liquid being conveyed is measured during a cycle of the filling phase of the container, and an alarm signal is emitted and/or the filling of the container is stopped if a measured maximum pressure in a cycle does not reach or does not exceed a limit value.

First claim

What is claimed is:

1. A method of filling a container that contains a concentrate, with the concentrate being provided so as to form a liquid concentrate or a part of a liquid concentrate on solution of the concentrate in, or dilution of the concentrate with, a liquid, the liquid concentrate or the part of a liquid concentrate being suitable for preparing a dialysis solution, and with the filling of the container taking place via a balance chamber system of a dialyzer which has a plurality of chambers from which the liquid is conveyed into the container in a form of repeating cycles, said method comprising:
prior to a blood treatment with the dialyzer, measuring a time development of the pressure of the liquid being conveyed from one of the plurality of chambers into the container during a cycle of the filling of the container, the time development of the pressure of the liquid corresponding to a magnitude of pressure pulses generated during an expulsion phase of the liquid; and
at least one of emitting an alarm signal, and stopping the filling of the container, if a measured maximum pressure in a cycle does not reach or does not exceed a limit value.

2. The method in accordance with claim 1 , wherein the balance chamber system of the dialyzer has at least two chambers, and an oscillating volume flows to and fro between the at least two chambers.

3. The method in accordance with claim 1 , wherein the limit value depends on a maximum value which was measured or which is predefined in a preceding cycle.

4. The method in accordance with claim 3 , wherein the limit value lies below a highest maximum pressure measured in the preceding cycle by a specific percentage or by a specific absolute value.

5. The method in accordance with claim 1 , wherein the limit value is not lowered during the filling.

6. The method in accordance with claim 1 , wherein the pressure of the liquid being conveyed is measured in a line between one of the plurality of chambers and the container, or in a line in communication with the line between the one of the plurality of chambers and the container.

7. The method in accordance with claim 1 , wherein the pressure of the liquid being conveyed first rises on an emptying of one of the plurality of chambers and then drops, and at least one of the alarm signal is emitted, and the filling of the container is stopped, when a lower limit value for the pressure is not reached, or is not fallen below, within a specific time window since the cycle start.

8. The method in accordance with claim 7 , wherein a specific time window for a first cycle or cycles is longer than for subsequent cycles.

9. The method in accordance with claim 1 , wherein at least one of a first cycle or cycles of a filling, and a last cycle, is not monitored before the stopping of the filling.

10. The method in accordance with claim 1 , wherein the container is vented to the atmosphere during the filling.

11. The method in accordance with claim 1 , wherein the limit value is only reset upon a confirmation or a recognition that a new container has been placed onto the dialyzer.

12. The method in accordance with claim 1 , wherein the concentrate located in the container is at least one of a liquid and a dry concentrate.

13. The method in accordance with claim 1 , wherein a gas is introduced into the container during the filling of the container with the liquid.

14. The method in accordance with claim 1 , wherein a new cycle is only initiated once a lower limit for the pressure of the liquid being conveyed has been reached if a specific minimum length of time has elapsed since the cycle start.

15. The method according to claim 1 , wherein the liquid is water.

16. The method according to claim 2 , wherein the oscillating volume corresponds to a volume of one of the at least two chambers.

17. The method according to claim 5 , wherein the limit value is not lowered if the measured maximum pressure is smaller in one cycle than in a previous cycle.

18. The method according to claim 12 , wherein the dry concentrate is a dry acid concentrate.

19. The method according to claim 13 , wherein the gas is air.

Assignees

• Fresenius Medical Care Deutschland Gmbh

Inventors

• Kloeffel Peter
• Nicholas Olaf

Classifications

• B67C3/287 Primary

  related to flow control using predetermined or real-time calculated parameters · CPC title

• A61M2205/15

  Detection of leaks · CPC title

• A61M2205/3331

  Pressure; Flow · CPC title

• A61M1/1635

  with volume chamber balancing devices between used and fresh dialysis fluid · CPC title

• A61M2205/18

  with alarm · CPC title