Systems and methods for processing sensor data

Patent metadata

Field	Value
Publication number	US-10506982-B2
Application number	US-201313899905-A
Country	US
Kind code	B2
Filing date	May 22, 2013
Priority date	Dec 17, 2007
Publication date	Dec 17, 2019
Grant date	Dec 17, 2019

Abstract

Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

First claim

What is claimed is:

1. A system for processing continuous analyte sensor data, comprising:
a continuous analyte sensor configured to continuously measure a concentration of an analyte in a host;
a computer system configured to receive sensor data from the continuous analyte sensor and to calibrate sensor data using calibration information, which is derived from an existing calibration set comprising a plurality of matched data pairs, each matched data pair comprising an analyte sensor signal and a corresponding analyte concentration, wherein the computer system is further configured to determine a predictive accuracy of the calibrated sensor data, wherein the predictive accuracy is a measure of an accuracy of prediction of a newly received matched data pair based on the calibration information derived from the existing calibration set that does not contain the newly received matched data pair, to compare the determined predictive accuracy with one or more accuracy level thresholds to produce an accuracy output, and to output the accuracy output; and
an insulin delivery device controlled by insulin delivery instructions and/or insulin therapy instructions to control insulin delivery, wherein the insulin delivery instructions and/or insulin therapy instructions are based at least in part on the accuracy output.

2. The system of claim 1 , wherein the one or more accuracy level thresholds delineate at least two predetermined ranges of accuracy.

3. The system of claim 1 , wherein the one or more accuracy level thresholds delineate at least three predetermined ranges of accuracy.

4. The system of claim 1 , wherein the computer system is configured to control insulin delivery instructions and/or insulin therapy instructions to a user interface for display based on the accuracy output.

5. The system of claim 1 , wherein the computer system is configured to control insulin delivery instructions and/or insulin therapy instructions using a transmission based on the accuracy output.

6. The system of claim 1 , wherein the computer system is configured to control insulin delivery instructions and/or insulin therapy instructions by determining when to trigger a failsafe in a closed loop insulin delivery system based on the accuracy output.

7. The system of claim 1 , wherein the computer system is configured to control insulin delivery instructions and/or insulin therapy instructions by requesting user interaction in a closed loop insulin delivery system based on the accuracy output.

8. A method for processing continuous analyte sensor data, comprising:
receiving sensor data from a continuous analyte sensor, the sensor data comprising one or more sensor data points;
calibrating the sensor data using calibration information, which is derived from a first calibration set comprising a plurality of matched data pairs, each matched data pair comprising an analyte sensor signal and a corresponding analyte concentration;
on a processor, determining a predictive accuracy of the calibrated sensor data, wherein the predictive accuracy is evaluated by a difference between a first calibration line formed from the first calibration set and a second calibration line formed from a second calibration set containing a newly received matched data pair not contained in the first calibration set;
on the processor, comparing the determined predictive accuracy with one or more accuracy level thresholds to produce an accuracy output;
outputting the accuracy output; and
controlling an insulin delivery device using insulin delivery instructions and/or insulin therapy instructions to control insulin delivery, wherein the insulin delivery instructions and/or insulin therapy instructions are based at least in part on the accuracy output.

9. The method of claim 8 , wherein the one or more accuracy level thresholds delineate at least two predetermined ranges of accuracy.

10. The method of claim 8 , wherein the one or more accuracy level thresholds delineate at least three predetermined ranges of accuracy.

11. The method of claim 8 , wherein the determining the predictive accuracy is performed on calibrated sensor data in units of blood glucose concentration.

12. The method of claim 8 , wherein the insulin delivery device is an insulin pump.

13. The method of claim 8 , wherein the controlling the insulin delivery device using the insulin delivery instructions and/or insulin therapy instructions comprises displaying, on a user interface, the insulin delivery instructions and/or insulin therapy instructions.

14. The method of claim 8 , wherein the controlling the insulin delivery device using the insulin delivery instructions and/or insulin therapy instructions comprises transmitting the insulin delivery instructions and/or insulin therapy instructions.

15. The method of claim 8 , wherein the controlling the insulin delivery device using the insulin delivery instructions and/or insulin therapy instructions comprises determining when to trigger a failsafe in a closed loop insulin delivery system.

16. The method of claim 8 , wherein the controlling the insulin delivery device using the insulin delivery instructions and/or insulin therapy instructions comprises requesting user interaction in a closed loop insulin delivery system.

Assignees

• Dexcom Inc

Inventors

• Kamath Apurv Ullas
• Mensinger Michael Robert
• Li Ying
• Mahalingam Aarthi
• Dobbles J Michael

Classifications

• G16H20/10

  relating to drugs or medications, e.g. for ensuring correct administration to patients · CPC title

• G16H40/63

  for local operation · CPC title

• A61B2560/0223

  of calibration, e.g. protocols for calibrating sensors · CPC title

• G16H50/50

  for simulation or modelling of medical disorders · CPC title

• A61B5/01

  Measuring temperature of body parts {; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue} (clinical contact thermometers G01K13/20) · CPC title