Lozenge dosage form having a disintegrative tablet portion and a candy glass shell portion

Patent metadata

Field	Value
Publication number	US-10500155-B2
Application number	US-201815879740-A
Country	US
Kind code	B2
Filing date	Jan 25, 2018
Priority date	May 22, 2017
Publication date	Dec 10, 2019
Grant date	Dec 10, 2019

Abstract

The present invention relates to a lozenge dosage form having a disintegrative tablet portion and a candy glass shell portion.

First claim

The invention claimed is:

1. A lozenge dosage form comprising:
a disintegrative tablet portion; and
a candy glass shell portion;
wherein the disintegrative tablet portion comprises at least one pharmaceutically active ingredient;
wherein the disintegrative tablet portion has a form of a plug as depicted in FIG. 3 ;
wherein the plug is added to the candy glass shell portion after the candy glass shell portion is formed;
wherein pressure and/or heat is added to the plug to fill in a predefined space within the candy glass shell portion;
wherein the candy glass shell portion has a form of a spherical cap as depicted in FIG. 1 ; and
wherein when combined the disintegrative tablet portion and the candy glass shell portion have a form as depicted in FIG. 2 .

2. The lozenge dosage form of claim 1 , wherein the candy glass shell portion comprises at least one pharmaceutically active ingredient.

3. The lozenge dosage form of claim 1 , wherein the disintegrative tablet portion comprises at least two excipients selected from the group consisting of a poloxamer, polyethylene glycol, a sugar, a starch and a starch hydrosylate.

4. The lozenge dosage form of claim 1 , wherein the disintegrative tablet portion comprises multiple layers.

5. The lozenge dosage form of claim 4 , wherein the disintegrative tablet portion comprises two layers, wherein a first layer comprises a first pharmaceutically active ingredient, and wherein a second layer comprises a second pharmaceutically active ingredient.

6. The lozenge dosage form of claim 5 , wherein the first layer and the second layer are exposed on a surface of the dosage form.

7. A method of treating an ailment comprising orally administering the lozenge dosage form of claim 1 .

Assignees

• Johnson & Johnson Consumer Inc

Inventors

• Mcnally Gerard P
• Koll Gregory
• Anderson Oliver

Classifications

• A61K9/209

  containing drug in at least two layers or in the core and in at least one outer layer · CPC title

• A23V2250/5118

  Starch · CPC title

• A23V2002/00

  Food compositions, function of food ingredients or processes for food or foodstuffs · CPC title

• A23G3/38

  Sucrose-free products · CPC title

• A23V2250/6422

  Xylitol · CPC title