Metal salt compositions
US-9486396-B2 · Nov 8, 2016 · US
Oral care compositions
US10500142B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10500142-B2 |
| Application number | US-201615393807-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 29, 2016 |
| Priority date | Dec 30, 2015 |
| Publication date | Dec 10, 2019 |
| Grant date | Dec 10, 2019 |
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- Title
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Abstract
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Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride and a pyrophosphate salt and oral care compositions comprising the complexes and uses thereof.
First claim
Opening claim text (preview).
What is claimed is: 1. An oral care composition comprising an aqueous soluble tin phosphate complex formed from a mixture comprising tin (II) fluoride, and a pyrophosphate salt; wherein the complex comprises tin, phosphate and fluoride; and wherein the complex is formed from a mixture comprising the tin (II) fluoride and pyrophosphate salt in a molar ratio of 1P:1Sn to 10P:1Sn, and wherein the complex is present in an amount of 2 to 30 weight % by weight of the composition, wherein the complex is formed in situ in an aqueous solution and combined with an oral care base, or wherein the complex is isolated from the aqueous solution in solid form and combined with the oral care base, or wherein the complex is lyophilized and combined with the oral care base, or wherein the complex is isolated with an anti-solvent and combined with the composition. 2. The composition of claim 1 , wherein the oral care base is a mouthwash base, an oral gel or a dentifrice base. 3. The composition of claim 1 , wherein the complex is formed from a mixture comprising 1 to 10 weight % tin (II) fluoride by weight of the mixture and 1 to 40 weight % pyrophosphate salt by weight of the mixture. 4. The composition of claim 1 , wherein the pyrophosphate salt is tetrapotassium pyrophosphate (K 4 P 2 O 7 ). 5. The composition of claim 4 , wherein the complex is formed from a mixture comprising the tin (II) fluoride and tetrapotassium pyrophosphate in a molar ratio of at least 1P:1Sn. 6. The composition of claim 4 , wherein the complex is formed from a mixture comprising the tin (II) fluoride and tetrapotassium pyrophosphate in a molar ratio of 1P:1Sn to 10P:1Sn. 7. The composition of claim 4 , wherein the complex is formed from a mixture comprising 1 to 10 weight % tin (II) fluoride by weight of the mixture and 1 to 40 weight % tetrapotassium pyrophosphate by weight of the mixture. 8. The composition of claim 1 , wherein the pyrophosphate salt is tetrasodium pyrophosphate (Na 4 P 2 O 7 ). 9. The composition of claim 8 , wherein the complex is formed from a mixture comprising the tin (II) fluoride and tetrasodium pyrophosphate in a molar ratio of 1P:1Sn to 5P:1Sn. 10. The composition of claim 8 , wherein the complex is formed from a mixture comprising 1 to 10 weight % tin (II) fluoride by weight of the mixture and 1 to 30 weight % tetrasodium pyrophosphate by weight of the mixture. 11. The composition of claim 8 , wherein the tin (II) fluoride and tetrasodium pyrophosphate (Na 4 P 2 O 7 ) form a complex having the formula [P 2 O 7 ] 4− Na 2+ Sn 2+ 2 F − . 12. The composition of claim 1 , wherein the composition comprises an aqueous solution. 13. The composition of claim 1 further comprising more than 20 weight % water by weight of the composition. 14. The composition of claim 1 , wherein the composition is a mouthwash. 15. The composition of claim 1 for use to reduce dentinal hypersensitivity. 16. A method to reduce or inhibit dentinal hypersensitivity, dental caries, gingivitis, or plaque in a person in need thereof comprising applying an effective amount of an oral care composition as claimed in claim 1 to teeth of the person.
Assignees
Inventors
Classifications
Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses · CPC title
Metal complex; Coordination compounds · CPC title
containing inorganic ingredients · CPC title
- A61K8/24Primary
Phosphorous; Compounds thereof · CPC title
Fluorides; Derivatives thereof · CPC title
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- What does patent US10500142B2 cover?
- Provided are aqueous soluble tin phosphate complexes formed from a mixture comprising tin (II) fluoride and a pyrophosphate salt and oral care compositions comprising the complexes and uses thereof.
- Who is the assignee on this patent?
- Colgate Palmolive Co
- What technology area does this patent fall under?
- Primary CPC classification A61K8/24. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Dec 10 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 7 related publications on this page (citations in our corpus or others sharing the same primary CPC).