Synthetic peptide, and cosmetic composition or pharmaceutical composition and application thereof
US-2024352069-A1 · Oct 24, 2024 · US
Pediococcus acidilactici derived antimicrobial hexapeptide and preparation method thereof
US10487112B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-10487112-B2 |
| Application number | US-201615746596-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 8, 2016 |
| Priority date | Aug 25, 2016 |
| Publication date | Nov 26, 2019 |
| Grant date | Nov 26, 2019 |
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- Title
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Abstract
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A Pediococcus acidilactici derived antimicrobial hexapeptide and a preparation method thereof are disclosed herein. The antimicrobial peptide ENGEEE (SEQ ID NO: 1) is reported for the first time. Antimicrobial peptide lactein R16 has good pH stability and thermal stability, has an effect on inhibiting Escherichia coli, Listeria monocytogenes and Staphylococcus aureus and is capable of effectively reducing the amount of the Escherichia coli in soybean meal. Secondly, the antimicrobial peptide lactein R16 has a certain effect on proliferating Saccharomyces cerevisiae and Lactobacillus plantarum and has certain capability of clearing hydrogen peroxide, hydroxyl radicals, DPPH radicals and superoxide anions. The antimicrobial peptide lactein R16 can be used for biological control and can be used as a feed additive to play important roles in substituting antibiotics and solving the feed safety problem.
First claim
Opening claim text (preview).
What is claimed is: 1. A composition comprising an antimicrobial peptide consisting of the amino acid sequence of SEQ ID NO: 1, and a soybean meal. 2. The composition of claim 1 , further comprising Escherichia coli. 3. A method of inhibiting bacterial infection in a subject, comprising administering the composition of claim 1 to the subject in need thereof. 4. The method of claim 3 , wherein the bacterial infection is selected from the group consisting of Escherichia coli, Listeria monocytogenes and Staphylococcus aureus.
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Classifications
Amino acids; Peptides; Protein hydrolysates; Nucleic acids; Derivatives thereof · CPC title
N-acyl derivatives · CPC title
Microorganisms; Enzymes; {Antibiotics} · CPC title
Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation · CPC title
Polymeric derivatives, e.g. peptides or proteins · CPC title
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- What does patent US10487112B2 cover?
- A Pediococcus acidilactici derived antimicrobial hexapeptide and a preparation method thereof are disclosed herein. The antimicrobial peptide ENGEEE (SEQ ID NO: 1) is reported for the first time. Antimicrobial peptide lactein R16 has good pH stability and thermal stability, has an effect on inhibiting Escherichia coli, Listeria monocytogenes and Staphylococcus aureus and is capable of effective…
- Who is the assignee on this patent?
- Univ Jiangnan
- What technology area does this patent fall under?
- Primary CPC classification C07K7/06. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Nov 26 2019 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).