Medical fluid injector

Patent metadata

Field	Value
Publication number	US-10478558-B2
Application number	US-201615375481-A
Country	US
Kind code	B2
Filing date	Dec 12, 2016
Priority date	Mar 15, 2013
Publication date	Nov 19, 2019
Grant date	Nov 19, 2019

Abstract

Systems and methods for intelligently delivering fluid to a targeted tissue are described. The systems and methods may include directing a pump to distribute fluid to a targeted tissue and receiving one or more signals from an intracorporeal sensing system, where the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue. The systems and methods may also include determining whether the one or more sensed feedback parameters are within an acceptable range. If the one or more sensed feedback parameters are not within the acceptable range, the systems and methods may include determining an adjusted velocity for the plunger necessary to adjust the pressure of the fluid in the pump so that the one or more sensed feedback parameters move within the acceptable range and directing the pump to distribute the fluid at the adjusted velocity.

First claim

The invention claimed is:

1. A system for delivering a fluid to a targeted tissue, the system comprising:
a pump configured to contain a volume of fluid at a pressure, wherein the pressure of the fluid is in a range of about 10 psi to about 2000 psi prior to distribution of the fluid to the targeted tissue;
a processor;
an intracorporeal sensing system in operable communication with the processor; and
a non-transitory, processor-readable storage medium in communication with the processor, wherein the non-transitory, processor-readable storage medium contains one or more programming instructions that, when executed, cause the processor to:
direct the pump to distribute the fluid to the targeted tissue at an initial velocity;
receive one or more signals from the intracorporeal sensing system, wherein the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue, wherein the one or more sensed feedback parameters comprise one or more of a pressure in a receiving vessel, a pressure in the targeted tissue, an image property, a tissue stretch property, a tissue conductivity, a tissue ultrasound property, a flow rate in the targeted tissue, a fluid cell count, a fluid particle count, and a density of a measurable tracer;
determine whether the one or more sensed feedback parameters are within an acceptable range;
if the one or more sensed feedback parameters are not within the acceptable range, determine an adjusted velocity; and
direct the pump to distribute the fluid at the adjusted velocity.

2. The system of claim 1 , further comprising one or more programming instructions, that, when executed, direct the processor to:
receive one or more inputs, wherein the one or more inputs correspond to data that defines the acceptable range.

3. The system of claim 1 , further comprising:
a display in operable communication with the processor; and
one or more programming instructions that, when executed, direct the processor to:
direct the display to display one or more of data corresponding to the acceptable range in a user-readable format and the one or more sensed feedback parameters in a user-readable format.

4. The system of claim 1 , further comprising:
one or more driving devices in operable communication with the processor; and
an actuation component mechanically connected to the one or more driving devices and the pump,
wherein the one or more programming instructions that, when executed, cause the processor to direct the pump to distribute the fluid to the targeted tissue further comprise one or more programming instructions that, when executed, cause the processor to activate the one or more driving devices to cause the actuation component to direct the pump to distribute the fluid to the targeted tissue.

5. The system of claim 1 , wherein:
the pump is a syringe body; and
the system further comprises a pressure jacket configured to surround the syringe body and prevent the syringe body from expanding.

6. The system of claim 5 , further comprising an end plug connected to a distal portion of the syringe body, wherein the end plug:
is formed of a solid piece of material;
comprises a bore therethrough for accurate distribution of the fluid; and
is configured to prevent leakage of the fluid from the syringe body.

7. The system of claim 1 , wherein the volume of fluid is in a range of about 10 mL to about 2000 mL prior to distribution of the fluid to the targeted tissue.

8. The system of claim 1 , wherein the intracorporeal sensing system comprises a sensor that is disposed at or near the targeted tissue.

9. The system of claim 1 , wherein the one or more sensed feedback parameters are selected from the group consisting of a tissue stretch property, a tissue conductivity, a tissue ultrasound property, a flow rate in the targeted tissue, a fluid cell count, a fluid particle count, and a density of a measurable tracer.

10. The system of claim 1 , further comprising one or more programming instructions, that, when executed, direct the processor to:
monitor at least one other of the one or more of the sensed feedback parameters while the pump distributes the fluid to the targeted tissue at the adjusted velocity to ensure the at least one other of the one or more of the sensed feedback parameters remains within the acceptable range.

11. The system of claim 10 , further comprising one or more programming instructions, that, when executed, direct the processor to:
if the at least one other of the one or more of the sensed feedback parameters is not within the acceptable range during the directing the pump to distribute the fluid to the targeted tissue at the adjusted velocity programming instruction, direct the system to perform at least one process selected from the group consisting of: alert a user that the at least one other of the one or more of the sensed feedback parameters is approaching a limit of the acceptable range, control the adjusted velocity so that the at least one other of the one or more of the sensed feedback parameters returns to the acceptable range, alert the user that the at least one other of the one or more of the sensed feedback parameters is outside the acceptable range and hold the adjusted velocity, alert the user that the at least one other of the one or more of the sensed feedback parameters is outside the acceptable range and require an action by the user, and stop the injection.

12. A method for delivering a fluid to a targeted tissue, the method comprising:
directing, by a processor, a pump to distribute the fluid to the targeted tissue at an initial velocity and at a pressure in a range of about 10 psi to about 2000 psi;
receiving, by the processor, one or more signals from an intracorporeal sensing system, wherein the one or more signals correspond to one or more sensed feedback parameters at the targeted tissue, wherein the one or more sensed feedback parameters comprise one or more of a pressure in a receiving vessel, a pressure in the targeted tissue, an image property, a tissue stretch property, a tissue conductivity, a tissue ultrasound property, a flow rate in the targeted tissue, a fluid cell count, a fluid particle count, and a density of a measurable tracer;
determining, by the processor, whether the one or more sensed feedback parameters are within an acceptable range;
if the one or more sensed feedback parameters are not within the acceptable range, determining, by the processor, an adjusted velocity; and
directing, by the processor, the pump to distribute the fluid to the targeted tissue at the adjusted velocity.

13. The method of claim 12 , further comprising:
receiving, by the processor, one or more inputs, wherein the one or more inputs correspond to data that defines the acceptable range.

14. The method of claim 12 , further comprising directing, by the processor, a display to display one or more of data corresponding to the acceptable range in a user-readable format and the one or more sensed feedback parameters in the user-readable format.

15. The method of claim 12 , wherein directing the pump to distribute the fluid to the targeted tissue further comprises causing, by the processor, one or more driving devices to activate, wherein activation of the one or more driving devices causes an actuation component to direct the pump to distribute the fluid to the targeted tissue.

16. The method of claim 12 , wherein directing the pump to distribute the fluid to the targeted tissue further comprises directing the pump to distribute a volume of fluid in the range of about 10 mL to about 2000 mL t

Assignees

• Bayer Healthcare Llc

Inventors

• Uram Martin J
• Yanniello Michael J
• Tucker Barry L
• Mishler David A
• Rhinehart Edward J
• Trocki Mark
• Uber Iii Arthur E
• Cowan Kevin P
• Brosovich John A

Classifications

• A61M2205/52

  with memories providing a history of measured variating parameters of apparatus or patient · CPC title

• A61M5/14566

  with a replaceable reservoir for receiving a piston rod of the pump · CPC title

• A61M5/1723 Primary

  using feedback of body parameters, e.g. blood-sugar, pressure (measurement of body parameters A61B5/00) · CPC title

• A61M5/1452

  pressurised by means of pistons · CPC title

• A61M2205/3576

  with non implanted data transmission devices, e.g. using external transmitter or receiver · CPC title