Device and method for treatment of incision or hernia

Patent metadata

Field	Value
Publication number	US-10478168-B2
Application number	US-201113294222-A
Country	US
Kind code	B2
Filing date	Nov 11, 2011
Priority date	Jul 2, 2009
Publication date	Nov 19, 2019
Grant date	Nov 19, 2019

Abstract

Devices and methods for treating an abdominal incision or hernia are described. An implant for the restoration or prophylactic treatment of an abdominal wall comprises an elongate element and at least one sheet connected to the elongate element along a longitudinal axis of the elongate element. The elongate element is positioned along the line of incision, and the at least one sheet is secured to the abdominal muscles surrounding the incision.

First claim

The invention claimed is:

1. A device for treating an incision, hernia, or abdominal wall defect, comprising:
an elongate element having a first longitudinal axis; and
at least one sheet connected to the elongate element along the first longitudinal axis;
wherein the at least one sheet comprises an acellular dermal tissue matrix derived from porcine dermis having a Young's modulus within a range of 49.5 MPa to 94.7 MPa.

2. The device of claim 1 , wherein the at least one sheet is connected to the elongate element along an approximate midline of the sheet.

3. The device of claim 1 , wherein the tissue is from an α1,3-galactosyltransferase (α1,3GT) deficient pig.

4. The device of claim 1 , wherein the elongate element comprises an acellular dermal tissue matrix.

5. The device of claim 4 , wherein the elongate element comprising the acellular dermal tissue matrix is rolled concentrically into a cylindrical structure.

6. The device of claim 1 , wherein the elongate element comprises a piece of acellular connective tissue.

7. The device of claim 6 , wherein the connective tissue is a tendon.

8. The device of claim 6 , wherein the connective tissue is a ligament.

9. The device of claim 1 , wherein the at least one sheet comprises multiple superimposed sheets.

10. The device of claim 1 , wherein the at least one sheet is divided into two halves when connected to the elongate element.

11. The device of claim 1 , wherein the at least one sheet is connected to the elongate element using surgical sutures.

12. The device of claim 1 , wherein the biomechanical strength of the at least one sheet is equal to that of the elongate element.

13. A method of closing a midline incision, comprising the steps of:
providing an implant comprising an elongate element having a first longitudinal axis and at least one sheet connected to the elongate element along the first longitudinal axis, wherein the at least one sheet comprises an acellular dermal tissue matrix derived from porcine dermis having a Young's modulus within a range of 49.5 MPa to 94.7 MPa;
positioning the elongate element along the midline incision; and
positioning the at least one sheet on at least one of an anterior side and a posterior side of a rectus abdominis muscle surrounding the midline incision.

14. The method of claim 13 , further comprising the step of creating spaces on the anterior or posterior sides of the rectus abdominis muscle for placement of the at least one sheet.

15. The method of claim 13 , further comprising the step of suturing the at least one sheet to the rectus abdominis muscle.

16. The method of claim 13 , wherein the at least one sheet is inserted between an anterior layer of fascia and the rectus abdominis muscle.

17. The method of claim 13 , wherein the at least one sheet is inserted between a posterior layer of fascia and the rectus abdominis muscle.

18. The method of claim 13 , wherein the at least one sheet is inserted over an anterior layer of fascia.

19. The method of claim 13 , wherein the at least one sheet is inserted below a posterior layer of fascia.

20. The method of claim 13 , wherein the acellular dermal tissue matrix is treated to remove antigens that are immunogenic to a human recipient.

21. The method of claim 13 , wherein the elongate element comprises a piece of acellular connective tissue.

22. The method of claim 21 , wherein the connective tissue comprises a tendon.

23. The method of claim 21 , wherein the connective tissue comprises a ligament.

24. The method of claim 13 , wherein the at least one sheet has a biomechanical strength that is equal to that of the elongate element.

25. The method of claim 13 , wherein the at least one sheet has a stretchability that is equal to that of the elongate element.

Assignees

• Sun Wenquan
• Monteiro Gary
• Lifecell Corp

Inventors

• Sun Wenquan
• Monteiro Gary

Classifications

• A61F2/0063

  Implantable repair or support meshes, e.g. hernia meshes · CPC title

• A61B17/0057 Primary

  Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect (sutures A61B17/04; closing rectum or urethra near body surface A61F2/0009) · CPC title

• A61L31/005

  Ingredients of undetermined constitution or reaction products thereof · CPC title

• A61B17/0469

  Suturing instruments for use in minimally invasive surgery, e.g. endoscopic surgery · CPC title

• A61B2017/00606

  Implements H-shaped in cross-section, i.e. with occluders on both sides of the opening · CPC title