System and method to efficiently clean a blood filter

Patent metadata

Field	Value
Publication number	US-10463775-B2
Application number	US-201815980387-A
Country	US
Kind code	B2
Filing date	May 15, 2018
Priority date	Jan 8, 2013
Publication date	Nov 5, 2019
Grant date	Nov 5, 2019

Abstract

A renal therapy apparatus includes a blood filter, a blood pump, a treatment fluid pump, and a control unit configured to control at least one of the blood pump or the treatment fluid pump during a filter cleaning sequence. In a first phase of the filter cleaning sequence, a first fluid including a blood-compatible and physiologically safe fluid is transferred back and forth across the insides and/or outsides of the blood filter. After the first phase, a second fluid is formed by mixing the first fluid with air. In a second phase of the filter cleaning sequence, the second fluid is transferred across the insides and/or outsides of the blood filter at least one time.

First claim

The invention is claimed as follows:

1. A renal therapy apparatus comprising:
a blood filter including a plurality of hollow fiber membranes;
arterial and venous lines in fluid communication with the blood filter;
a blood pump for pumping blood through the arterial and venous lines and the blood filter;
a treatment fluid pump in fluid communication with (a) a treatment fluid side of the blood filter or (b) the arterial or venous line;
a control unit configured to control the blood pump and the treatment fluid pump during a blood treatment of a patient and at least one of the blood pump or the treatment fluid pump during a filter cleaning sequence in which
(i) in a first phase of the filter cleaning sequence, a first fluid including a blood-compatible and physiologically safe fluid is transferred back and forth across the insides and/or outsides of the plurality of hollow fiber membranes,
(ii) after the first phase, a second fluid is formed by mixing the first fluid with air, and
(iii) in a second phase of the filter cleaning sequence, the second fluid is transferred across the insides and/or outsides of the plurality of hollow fiber membranes at least one time,

wherein the use of the first and second fluids including the blood-compatible and physiologically safe fluid enables the filter cleaning sequence to be performed during the blood treatment, and
wherein the first and second fluids are delivered to the blood filter instead of a drain during (i), (ii), and (iii).

2. The renal therapy apparatus of claim 1 , wherein at least one of the first or second fluids is configured to loosen or remove blood residuals from the hollow fiber membranes.

3. The renal therapy apparatus of claim 1 , which includes a filtered air access in fluid communication with a valve, the control unit configured to control the valve to selectively allow the air in to be mixed in (ii).

4. The renal therapy apparatus of claim 1 , wherein the treatment fluid pump is a replacement fluid pump and the blood-compatible and physiologically safe fluid is a replacement fluid that is pumped by the replacement fluid pump, and
wherein the control unit controls the replacement fluid pump to perform at least one of (i), (ii), or (iii).

5. The renal therapy apparatus of claim 1 , wherein the treatment fluid pump is a fresh dialysate fluid pump, and wherein the blood-compatible and physiologically safe fluid is dialysate that is pumped by the fresh dialysate fluid pump.

6. The renal therapy apparatus of claim 1 , which includes a saline supply in fluid communication with the arterial or venous line, and wherein the blood pump or the treatment fluid pump is positioned and arranged to pump saline from the saline supply.

7. The renal therapy apparatus of claim 1 , wherein the control unit is configured to cause the blood pump to perform (i) to (iii) and the treatment fluid pump to be operated during at least one of (i) and (iii) on the outsides of the hollow fiber membranes in an attempt to equalize pressure across the hollow fiber membranes.

8. The renal therapy apparatus of claim 1 , wherein the control unit is configured to cause only the blood pump to perform (i) to (iii).

9. The renal therapy apparatus of claim 1 , wherein the control unit is configured to cause the blood pump and the treatment fluid pump to perform (i) and (ii) and the blood pump only to perform (iii).

10. The renal therapy apparatus of claim 1 , wherein the blood filter is a dialyzer.

11. The renal therapy apparatus of claim 1 , which is configured to transfer the second fluid to the drain after the second phase.

12. A renal therapy apparatus comprising:
a blood filter including a plurality of hollow fiber membranes;
a blood pump for pumping blood through the blood filter;
a treatment fluid pump in fluid communication with a treatment fluid side of the blood filter;
a selective air access; and
a control unit configured to control the blood pump and the treatment fluid pump during a blood treatment of a patient and at least one of the blood pump or the treatment fluid pump during a filter cleaning sequence in which
(i) in a first phase of the filter cleaning sequence, a first fluid including a blood-compatible and physiologically safe fluid is transferred back and forth across the insides and/or outsides of the plurality of hollow fiber membranes,
(ii) after the first phase, a second fluid is formed by mixing the first fluid with air via the selective air access, and
(iii) in a second phase of the filter cleaning sequence, the second fluid is transferred across the insides and/or outsides of the plurality of hollow fiber membranes at least one time,

wherein the control unit is configured to enable the filter cleaning sequence to be performed during the blood treatment using the first and second fluids, and
wherein the first and second fluids are delivered to the blood filter instead of a drain during (i), (ii), and (iii).

13. The renal therapy apparatus of claim 12 , wherein the selective air access is at least one of (i) vented via a protective membrane or (ii) selectively accessed via a valve.

14. A method for cleaning a blood filter during a cleaning sequence comprising:
(i) during a first phase of the cleaning sequence, pumping a first fluid including a blood-compatible and physiologically safe fluid back and forth across the insides and/or the outsides of a plurality of hollow fiber membranes of the blood filter so as to remove or loosen blood residuals, such as blood clots, proteins and/or biological fluid;
(ii) after the first phase, forming a second fluid by injecting air into the blood-compatible and physiologically safe fluid;
(iii) during a second phase of the cleaning sequence, pumping the second fluid across the insides and/or outsides of the plurality of the hollow fiber membranes of the blood filter to further remove or loosen blood residuals therefrom,
wherein the first and second fluids are delivered to the blood filter instead of a drain during (i), (ii), and (iii); and
(iv) after the second phase, transferring the second fluid along with the removed or loosened blood residuals to the drain,
wherein the use of the first and second fluids including the blood-compatible and physiologically safe fluid enables the cleaning sequence to be performed during a blood treatment.

15. The method of claim 14 , wherein pumping the second fluid across the insides and/or outsides of the membranes includes at least one of (a) breaking the air into microbubbles, (b) pumping the second fluid from a bottom of the blood filter to a top of the blood filter, (c) pumping the second fluid back and forth across the membranes, or (d) circulating the second fluid across the membranes a plurality of times.

16. The method of claim 14 , wherein transferring the second fluid to the drain includes injecting air to push the second fluid along with the removed or loosened blood residuals to the drain.

17. The method of claim 14 , which further includes priming the blood filter with at least one of dialysate, replacement fluid, or saline after the transferring performed in (iv).

18. The method of claim 14 , which further includes disinfecting the blood filter with at least one of hot water or a chemical disinfectant after the transferring performed in (iv).

19. The method of claim 14 , wherein the cleaning sequence is performed at the end of the blood treatment during a rinseback of blood to the patient.

20. The method of claim 14 , wherein injecting air includes at least one of

Assignees

• Baxter Int
• Baxter Healthcare Sa

Inventors

• Rohde Justin
• Wiebenson Derek

Classifications

• A61M1/168 Primary

  Sterilisation or cleaning before or after use · CPC title

• A61M1/1688 Primary

  with recirculation of the sterilising fluid · CPC title

• A61M1/1686

  by heat · CPC title

• A61M1/169

  using chemical substances · CPC title

• A61M1/1682

  both machine and membrane module, i.e. also the module blood side · CPC title